All RNA articles
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PodcastAlphaGenome & the RNA world hypothesis
In this episode, we discuss Google DeepMind’s latest deep learning model AlphaGenome, dissect the origins of life from chemicals to complex lifeforms, and hear the latest headlines.
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ResearchThioesters could explain how proteins first formed on early Earth
Cells use proteins to make other proteins – new research could explain how the first proteins arose without other enzymes directing the process
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NewsNew UK facility to turbo-charge development of novel RNA therapies
Government to invest £30 million in RNA biofoundry to accelerate therapies for cancer and genetic disorders
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ResearchEasy to remove tag could make mRNA synthesis for vaccines quicker and cheaper
Chemical synthesis takes another step towards overtaking more complex enzymatic routes
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ResearchSelf-assembling RNA strands ‘tamed the chemical chaos’ in prebiotic mixtures
New research explores mechanisms that boost RNA’s stability and resistance to hydrolysis
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FeatureMore than a mirror-image: left-handed nucleic acids
Now a biological reality, researchers are starting to figure out the many roles of left-handed nucleic acids such as Z-DNA – from immunity to controlling our genetics. Rachel Brazil reports
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Research’This is just the beginning’: RNA editing set to democratise viral engineering
Crispr-based system could ease development of novel RNA therapies
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CareersWorking at the forefront of AI
Petrina Kamya’s curiosity has led her across sectors to become a leader in drug discovery
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ResearchRNA building block uracil recovered from near-Earth asteroid Ryugu
Japanese mission returns pristine sample to bolster idea that prebiotic chemicals could have been delivered by meteorites
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OpinionA promising breakthrough in liquid condensate compartmentalisation
Tears are RNA solvent droplets that could help engineer new functions into bacteria
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OpinionCracking codons
Understanding how chemistry links RNA triplets to the properties of amino acids
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OpinionFrom prebiotic soup to fine-grained RNA world
Theories about how life emerged need to be closely attuned to conditions on the early Earth
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ResearchFreeze–thaw cycles could explain how ancient RNA replicated without enzymes
Discovery solves puzzle of RNA world hypothesis
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ResearchAll of life’s nucleic acids could have extraterrestrial origins
All five nucleobases of RNA and DNA found in three meteorites
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NewsChemistry Nobel laureate Sidney Altman dies at 82
Canadian–American molecular biologist won the 1989 prize for discovering RNA’s catalytic ability
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FeatureSequencing one cell at a time
New advances that allow scientists to uncover the molecular differences between individual cells could revolutionise medicine, Ian le Guillou finds
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BusinessNew antiviral impresses against Covid-19
Merck & Co and Ridgeback’s molnupiravir reduces risk of hospitalisation and death, and may work against other coronaviruses
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NewsChemistry Nobel predictions range from free-radical chemistry to MOFs
Data-crunching goes up against gut feeling as the chemistry community weighs in on their favourites for the world’s top chemistry prize
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ResearchMachine learning accurately predicts RNA structures using tiny dataset
Development could lead to better understanding of RNA and new medicines
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ResearchNew class of biomolecule baffles scientists
GlycoRNAs found across several cell types and organisms