All RNA articles
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FeatureDrugging RNA
Some medicinal chemists have changed their focus from proteins to target RNA, finds Rachel Brazil
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Business
Early indications suggest Pfizer–BioNTech’s Covid-19 vaccine is effective
Company claims 90% efficacy at preventing disease, but experts call for data rather than press releases
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Research
Entirely new way of sensing iron discovered in bacteria
Novel class of riboswitches can directly and selectively sense iron
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Feature
Unnatural selection in chemical systems
Great strides have been made in the lab with chemical systems that ape life’s behaviour
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News
New Covid-19 test delivers diagnoses up to three time faster
Researchers at the University of Oxford claim their new coronavirus diagnostic technology is fast and highly accurate
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Business
RNA vaccines are coronavirus frontrunners
Several groups have potential Sars-CoV-2 vaccines ready or close to testing, thanks to rapid development pathways
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Research
Unified synthesis shows how genetic alphabet could have been put together on early Earth
Cycles of wet and then dry conditions provide the right conditions to make all the nucleobases from basic chemicals
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Research
Mineral surfaces promoted variation in prebiotic RNA
Thermodynamic model probes the entropic cost of enriching RNA strands adsorbed on a surface
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Research
Hepatitis C drug lead designed to target virus RNA
Gene-to-RNA-to-medicine pipeline possible thanks to technique that reveals interactions between RNA and small molecules
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Research
Scrutiny of SmartFlares raises questions over RNA probes
Merck Millipore technology for detecting specific RNAs may not live up to claims
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Business
Lilly and CureVac to collaborate on mRNA cancer vaccines
Deal could see CureVac net up to $1.8 billion in upfront and milestone payments
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Research
Crispr gene editor can now alter RNA as well as DNA
Gene editing technique is developing apace with two new technologies unveiled
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Opinion
Rise of the biologics
Antibodies, RNA and gene therapy don’t necessarily compete with small molecule drugs – and they all rely on chemistry
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Business
Silence Therapeutics and Alnylam in patent dispute
Suit alleges competitors need to license Silence patents relating to their drug cantidates
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Research
Gooey origins for RNA world
Viscous muddy pond edges may have been incubators for the rise of self-replicating RNAs on ancient Earth
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Research
Nucleic acid instability challenges RNA world hypothesis
Early life may have contained both RNA and DNA, rather than just RNA
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Opinion
How game theory could explain complex life
Philip Ball asks if the building blocks of life benefit from cooperation
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Research
Adenine and guanine synthesised using prebiotic pathway
Two of the nucleotide bases that make up genetic material have been formed in early Earth simulation experiments
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Research
Broken ribozyme comes to life
Low temperatures on early Earth may have helped RNA world organisms emerge
