All RNA articles
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Research
Unified synthesis shows how genetic alphabet could have been put together on early Earth
Cycles of wet and then dry conditions provide the right conditions to make all the nucleobases from basic chemicals
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Research
Mineral surfaces promoted variation in prebiotic RNA
Thermodynamic model probes the entropic cost of enriching RNA strands adsorbed on a surface
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Research
Hepatitis C drug lead designed to target virus RNA
Gene-to-RNA-to-medicine pipeline possible thanks to technique that reveals interactions between RNA and small molecules
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Research
Scrutiny of SmartFlares raises questions over RNA probes
Merck Millipore technology for detecting specific RNAs may not live up to claims
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Business
Lilly and CureVac to collaborate on mRNA cancer vaccines
Deal could see CureVac net up to $1.8 billion in upfront and milestone payments
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Research
Crispr gene editor can now alter RNA as well as DNA
Gene editing technique is developing apace with two new technologies unveiled
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Opinion
Rise of the biologics
Antibodies, RNA and gene therapy don’t necessarily compete with small molecule drugs – and they all rely on chemistry
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Business
Silence Therapeutics and Alnylam in patent dispute
Suit alleges competitors need to license Silence patents relating to their drug cantidates
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Research
Gooey origins for RNA world
Viscous muddy pond edges may have been incubators for the rise of self-replicating RNAs on ancient Earth
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Research
Nucleic acid instability challenges RNA world hypothesis
Early life may have contained both RNA and DNA, rather than just RNA
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Opinion
How game theory could explain complex life
Philip Ball asks if the building blocks of life benefit from cooperation
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Research
Adenine and guanine synthesised using prebiotic pathway
Two of the nucleotide bases that make up genetic material have been formed in early Earth simulation experiments
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Research
Broken ribozyme comes to life
Low temperatures on early Earth may have helped RNA world organisms emerge
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Research
Building blocks of life made in space ice simulations
Complex sugars – including the ‘backbone’ of RNA – have been created in lab-made interstellar ice
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Research
Lifting molecular brake may have kept primeval cells running
Removing RNA restriction can steady biochemical function, with relevance for life’s emergence
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News
Pressure on controversial nanoparticle paper builds
Expression of concern and reprimand for chemists may seal fate of work on palladium particles
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Research
Peptide glue may have held first protocell components together
Association between RNA and primitive membranes 4 billion years ago thought to have kick-started life could have been mediated by peptides
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Research
Ancient RNA enzymes formed from freeze-thaw cycles
Temperature cycles help small pieces of RNA assemble into complex ribozymes
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Research
SiRNA treatment cures Ebola in monkeys
Researchers perform the first successful trial for a drug against the current strain of Ebola
