Structural biology – Page 3
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FeatureArtificial photosynthesis: solar water splitting
The chemistry to mimic ones of nature’s greatest feats still has some hurdles to overcome
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ResearchFruit flies’ protective corneal coatings reproduced
Anti-reflective and anti-adhesive nano-coating that covers the eyes of insects could find uses in medical implants and contact lenses
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ResearchViewpoint shift designs drug binding proteins from scratch
New method focuses on the groups touching amino acid side chains
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OpinionBarbara Low, penicillin and the protein pi helix
Mike Sutton celebrates the remarkable career of a female crystallographer, once mistaken for the tea-lady
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ResearchDecoding the chemistry behind cicada’s bacteria-killing wings
Organisation and composition of nanostructures help to explain unique properties
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ResearchUnnatural cyclic amino acids push limits of ribosome
Expanding repertoire of monomers for ribosome-mediated polymerisation is boon for scientists wanting to harness nature’s protein factories
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ResearchPhotosynthesis rewired to generate hydrogen
Gene transplant repositions algal hydrogenase so that it directly captures electrons from photosystem I
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ResearchTrapped enzyme reveals its unexpected shape-shifting ability
Metamorphic protein confined in nanopore found to switch between different 3D shapes as it catalyses a redox reaction
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NewsScience steps up a gear as struggle to both understand and fight coronavirus intensifies
Research that might have taken years is being turned around in months as journals fast-track Covid-19 manuscripts
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ResearchStructural studies offer glimpse of how coronavirus initiates human cell invasion
Researchers studying virus receptor-binding domains suggest virus could have passed directly from bats to humans
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ResearchDNA instructions pack proteins into unique crystal structures
Process could aid discovery of materials that exploit specific protein functions, such as drug molecules or biocatalysts
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ResearchPotent coronavirus drug candidate designed using 3D structure of key viral enzyme
Inhibitor of Sars-CoV-2 protease shows promise in early animal tests
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FeatureUncovering how the spliceosome makes the cut
Clare Sansom looks at the complex world of the spliceosome, a molecular machine in all our cells
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ResearchDetailed 3D coronavirus spike map offers hope for vaccine development
Structure determined at ‘remarkable’ speed in little over a month
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Research‘Chemical ear defenders’ could prevent hearing loss
Discovery of receptor connected to hearing loss has led to a chemical compound that can protect the neuromechanical machinery in mice’s ears
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ResearchSugars designed to disrupt bacterial cell wall biosynthesis
Rare monosaccharides explore concept for new narrow-spectrum antibiotics
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ResearchEngineered insulin with enhanced thermal stability inspired by fish-hunting snails
Four-disulfide insulin has similar bioactivity to native human insulin
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NewsSwipe right to help in the fight against Huntington’s disease
Citizen science project improves understanding of protein misfolding disorders like Huntington’s and Alzheimer’s diseases
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ResearchSecret of super-tough scales of giant Amazonian fish uncovered
Spiral-staircase structure prevents the scales being penetrated by piranhas
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OpinionRichard Henderson: ‘I rejected the phone call, and then noticed it was from Sweden…’
The 2017 laureate tells his story