All click chemistry articles
-
PodcastClick chemistry marks 25 years & covalent bonding in the actinides
Click chemistry: it’s in the name. How has this unique discipline made its mark over the last quarter decade? And, we discuss new experimental evidence of how covalent bonding works in the actinides.
-
OpinionCelebrating click chemistry’s 25th birthday
The field ‘is nowhere near mature – if not in its infancy, then perhaps enjoying a highly active childhood’, says one of click chemistry’s orignators
-
Research25 years ago click chemistry changed science. What happened next?
Barry Sharpless and his team first introduced the concept of ‘clicking’ molecules together 25 years ago
-
OpinionClick chemistry, 25 years on
A quarter of a century since first introducing the concpet of ‘click’, one of its originators explains how it became a transformational tool for scientists
-
ResearchClick chemistry toolbox expanded with 'forbidden' C–C bond forming reaction
Copper-catalysed addition produces functional links that should be compatible with biological systems
-
ResearchChemists and linguists unite to encode Confucian proverb using sequence-defined polymers
Interdisciplinary collaboration tests how two encoding schemas preserve the visual details of Chinese characters
-
ResearchFast flow-chemistry set-up facilitates sulfur-fluoride click chemistry
A modular method makes the most of flow-chemistry to create click-ready reagents selectively and efficiently
-
OpinionThe day my supervisor won the Nobel prize in chemistry
Celebrations and support in the Bertozzi lab
-
ResearchClick chemistry offers new, efficient process to produce unique cancer-fighting antibodies
Chemical approach is fast and flexible and could be an alternative o using protein engineering
-
ResearchPolymer upcycling strategy adds azide groups with electrocatalysis
Azido-modifications serve as diversification points for click transformations
-
ResearchIntroducing click chemistry’s newest reaction
Phosphorus fluoride exchange allows chemists to quickly build P–O and P–N linked compounds
-
ResearchClick chemistry with sound-induced mechanocatalysis
Researcher behind work says they ‘could be very close to a perfect way to conduct green chemistry’
-
FeatureHow click conquered chemistry
Katrina Krämer tells the story of how click and bioorthogonal chemistry came to win the 2022 Nobel prize
-
OpinionNobel vision
Looking beyond the here-and-now let click chemistry open up a whole new world of possibility
-
NewsExplainer: why have bioorthogonal and click chemistry won the 2022 Nobel prize?
Carolyn Bertozzi, Morten Meldal and Barry Sharpless have won the 2022 Nobel prize in chemistry – find out why
-
NewsNobel prize rewards click chemistry and bioorthogonal reactions
Barry Sharpless, Morten Meldal and Carolyn Bertozzi have been awarded the 2022 chemistry Nobel prize
-
ResearchRecord-breaking rotaxane prepared on polymer bead
Polystyrene beads decorated with 1014 rotaxane molecules
-
ResearchClick chemistry uses endogenous acrolein to activate cancer prodrug
Strategy could reduce chemotherapy side effects by selecting for cancerous cells
-
ResearchPlasmon-assisted click reaction reverses typical relationship between temperature and rate
Decrease in temperature seems to extend lifetime of plasma-induced excited states, which increases probability of reaction occurring
-
ResearchNMR findings suggest solution to enhanced diffusion dispute
Energy release rate may solve the puzzle of why the phenomenon is seen in some systems but not others