All click chemistry articles
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FeatureHow click conquered chemistry
Katrina Krämer tells the story of how click and bioorthogonal chemistry came to win the 2022 Nobel prize
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Opinion
Nobel vision
Looking beyond the here-and-now let click chemistry open up a whole new world of possibility
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News
Explainer: why have bioorthogonal and click chemistry won the 2022 Nobel prize?
Carolyn Bertozzi, Morten Meldal and Barry Sharpless have won the 2022 Nobel prize in chemistry – find out why
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News
Nobel prize rewards click chemistry and bioorthogonal reactions
Barry Sharpless, Morten Meldal and Carolyn Bertozzi have been awarded the 2022 chemistry Nobel prize
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Research
Record-breaking rotaxane prepared on polymer bead
Polystyrene beads decorated with 1014 rotaxane molecules
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Research
Click chemistry uses endogenous acrolein to activate cancer prodrug
Strategy could reduce chemotherapy side effects by selecting for cancerous cells
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Research
Plasmon-assisted click reaction reverses typical relationship between temperature and rate
Decrease in temperature seems to extend lifetime of plasma-induced excited states, which increases probability of reaction occurring
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Research
NMR findings suggest solution to enhanced diffusion dispute
Energy release rate may solve the puzzle of why the phenomenon is seen in some systems but not others
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Research
Surface sites on gold catalyst edited to control regioselectivity of a click reaction
Steric hindrance created by phosphine ligands restricts how substrates approach catalyst
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Business
Tissue scaffolds from resin inks
4D Medicine’s biodegradable polymer inks can be 3D-printed into useful biomedical applications
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Research
Alzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
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Research
Modified metallohelices show medical potential
Post-assembly click reactions on helical metal complexes produces biological activity akin to that of the arrow poison ouabain
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Research
Catalyst metal recovery adds greener notes to whisky production
Bacteria harnessed to make magnetite nanoparticles that can trap copper for click reactions
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Research
Erythropoietin benefits from controlled sugar-coating
Click chemistry allows glycosylation at virtually any synthetic stage
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Research
DNA synthesis is just a click away
The technique could be an efficient and cost-effective method of gene synthesis
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Research
Sulfur linkage takes click chemistry in a different direction
Thionyl tetrafluoride-based ‘sleeping beauties’ enable click chemistry in a tetrahedral shape
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Research
Click-on, click-off linkages join biochemical toolkit
Click chemistry reaction can be reversed ‘without a trace’
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Research
Unnatural nanoreactor puts click reaction in the spotlight
Engineered nanopore reveals long-lived ‘click chemistry’ intermediate
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Research
Firming COFs up takes Michael reaction catalysis forward
Chemists stabilise hexagonal layers that form nanochannels, which help speed up conversions
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Research
Click chemistry creates precision polymers
New synthesis technique allows the length and stereochemistry of artificial polymers to be controlled
