Crystallography – Page 4
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ResearchSalt bridge strategy expands access to pharmaceutical cocrystals
New approach to cocrystallisation could lead to exciting multi-drug combinations
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ResearchNanotubes enable first atomic-scale observation of nucleation’s baby steps
Single-walled carbon nanotubes and transmission electron microscope used to watch tiny metal crystals form in real time
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ArticleExploring the advantages of single-crystal x-ray diffraction in pharma
Single-crystal x-ray diffraction (SCXRD) in drug development is evolving. Johnson Matthey outlines how technology advances and regulations are reshaping its role in pharma
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OpinionBarbara Low, penicillin and the protein pi helix
Mike Sutton celebrates the remarkable career of a female crystallographer, once mistaken for the tea-lady
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ResearchNanodroplet encapsulation technique crystallises the ‘uncrystallisable’
High-throughput method that uses mere micrograms of small molecule samples could ease frustration for crystallographers
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ResearchStructural studies offer glimpse of how coronavirus initiates human cell invasion
Researchers studying virus receptor-binding domains suggest virus could have passed directly from bats to humans
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ResearchDNA instructions pack proteins into unique crystal structures
Process could aid discovery of materials that exploit specific protein functions, such as drug molecules or biocatalysts
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FeatureThe Middle East’s synchrotron is open Sesame
How difficult is it to build a world-class research facility in the Middle East? Kit Chapman investigates
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FeatureUncovering how the spliceosome makes the cut
Clare Sansom looks at the complex world of the spliceosome, a molecular machine in all our cells
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ResearchSodium ethoxide crystal structure solved after 180 years
Analysis of reagent commonly used in Claisen condensations and malonic ester synthesis
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ResearchTextbook structure rules formulated by Linus Pauling 90 years ago prove unreliable
Just 13% of 5000 oxides found to fulfil all five coordination geometry predictions
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ResearchReally random numbers created from crystals
Robot that monitors crystallization could lead to new ways to study stochastic processes in chemistry
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ResearchHigh-purity cubic phase offers new insight into ice physics
Cubic ice without stacking defects could help improve understanding of ice polymorphism
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ResearchYo-yo crystals are a new, rare kind of chiral porous material
Highly unusual structures possess chirality on molecular and macroscopic scales
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OpinionEllie Knaggs and tetrahedral carbon
Ellie Knaggs’ claim to be the first to use x-rays to prove carbon’s tetrahedral bonding in molecules has been overlooked, finds Andy Extance
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ResearchSemiconductive properties see subvalent silver oxide contravene textbook rules
Extreme synthetic conditions create material with a seemingly implausible electron count
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CareersStructuring a crystallographic database
Matt Lightfoot on navigating a career around the Cambridge Structural Database
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![An image showing the molecular structure of the [FeFe]-hydrogenase active site, the H-cluster](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/100x67/1/9/3/501193_index_834443.jpg)
ResearchNew setup enables EPR studies on tiny protein crystals
Experiments that normally takes five hours can now be done in just eight minutes
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OpinionHas x-ray had its day?
Will the giant of structure determination be toppled by blasts from electron beams?