When blood glucose levels are high, glucose displaces insulin loaded in the framework
Scientists have loaded an edible covalent organic framework (COF) with insulin and shown that it can sustainably reduce the blood glucose levels of diabetic rats. While there is still some way to go before the system could be used clinically, Ali Trabolsi of New York University Abu Dhabi, who led the work, is confident their system ‘will dramatically improve the well-being of diabetic patients worldwide in a very simple and straightforward way’ – by replacing multiple daily injections with pills.