All articles by Ian Le Guillou
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FeatureA new generation of materials inspired by teeth
Ian Le Guillou finds that some of nature’s toughest structures are helping scientists to develop new fibres that could revolutionise fabrics
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FeatureUsing genetics to personalise prescriptions
We’ve known for a long time that different people respond to certain drugs to very different extents, but now cheap DNA testing could make these disparities a thing of the past, as Ian Le Guillou reports
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FeatureSequencing one cell at a time
New advances that allow scientists to uncover the molecular differences between individual cells could revolutionise medicine, Ian le Guillou finds
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NewsResearch and regulations face-up to a new era of non-animal testing alternatives
Hopes raised that approval for skin sensitisation test could mark the start of a raft of in vitro toxicity tests
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FeatureHow the power of smell could identify new medical tests
Diagnosis by odour is nothing to be sniffed at, finds Ian Le Guillou
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FeatureGetting to the root of soil nitrogen
The farming industry’s reliance on nitrogen compounds is altering the environment, but Ian Le Guillou finds a better understanding of the interplay between plants and microbes could help to reduce the impact
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FeatureEngineering a handshake for proteins
Once considered undruggable, chemists are beginning to grasp protein–protein interactions, according to Ian Le Guillou
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BusinessDrop in plasma donations hits immunoglobulin supply
Lockdown and social distancing have discouraged donors, and the potential impact of convalescent plasma collection for Covid-19 treatment is unclear
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Research
A golden answer to drug competition
Ancient ratio found throughout nature may help to select the correct doses of medicine to use in combination
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ReviewResearch project success: the essential guide for science and engineering students
Getting good at research
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ReviewPrize fight
Morton MeyersPalgrave Macmillan2012 | 272pp | £16.99 (HB)ISBN 9780230338906While winners are written into the history books and their names synonymous with success, those in second place are quickly forgotten. This is as true in science as it is in sport. But assigning credit for scientific advances can be a tricky ...
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Research
Coral animal chemical structures solved
Elusive structures of two breitfussins cracked using atomic force microscopy
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Research
Call for 4G windfall to go to UK science
Top scientists back campaign to fund world class infrastructure and incentivise innovation
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NewsHow do you solve a problem like misconduct?
The world’s scientific bodies have come together to tackle fraud and plagiarism, but the problem will be tough to crack
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Research
A cell for a cell
A tiny jail that can hold a single biological cell could be a useful tool for studying rare cells
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Research
Night of the living surfaces
A work surface that 'feeds' on food spillages to synthesise antibiotics could help to prevent opportunistic infections in hospitals
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ResearchTurbo-charged Diels-Alder reaction
A new method for generating arynes from alkynes has been discovered via a Diels-Alder reaction
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News
Health check finds Canadian science doing well
Independent report says country’s research base is healthy, despite growing friction between scientists and government
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Research
Flattening the buckybowl
Adding 10 phenyl rings to corannulene has enabled researchers to turn it into a planar molecule
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ResearchSelf-assembling, squeezy nanotubes made
Nanotubes that pulsate as the temperature changes could be a useful new tool for nanotechnologists