Electrochemistry enables new, greener route to aromatic sulfonamides

One-step, metal-free, scalable route synthesises key functional group in drug discovery

Chemists in Germany have discovered a conceptually new and simple way to synthesise sulfonamides using electrochemistry. This new process avoids harsh conditions and allows chemists to directly functionalise aromatic moieties, without any prior treatment or modification. Moreover, the reaction could be scaled up to continuous systems, accelerating its industrial uptake.