Organic chemistry
The latest chemistry news and research on organic chemistry, including synthesis, natural products and total synthesis, reaction mechanisms and supramolecular chemistry, from the Royal Society of Chemistry's magazine, Chemistry World
-
OpinionJonathan Clayden: ‘I like to feel that we have set the curriculum rather than followed the curriculum’
The co-author of the much-loved Organic Chemistry shares his insights on creating a chemistry textbook
-
OpinionRewriting the textbooks – authors tell us how they do it
Peter Atkins, Catherine Housecroft and Jonathan Clayden guide us through the changing world of textbooks
-
OpinionWhat kinds of reactions do you do most?
Variety may be the spice of life, but there’s space for the boring but effective
-
ResearchMicrodroplet chemistry enables catalyst-free skeletal editing
Hydroxyl radicals power transformation of aniline into pyridine
-
ResearchOne-step photochemical method switches nitrogen and carbon to convert pyrazoles into imidazoles
Transformation tolerates a broad range of functional groups while preserving the peripheral substitution of the heterocycle
-
ResearchPEGylated ligands boost speed and selectivity in mechanochemical arylations
Study highlights the power of tailoring ligands to mechanochemical conditions
-
PodcastClick chemistry marks 25 years & covalent bonding in the actinides
Click chemistry: it’s in the name. How has this unique discipline made its mark over the last quarter decade? And, we discuss new experimental evidence of how covalent bonding works in the actinides.
-
NewsSurprising oxidising power of carbon dioxide freed by photochemistry
Iron-based photocatalyst enabled a range of useful organic molecules to be synthesised from alkenes
-
OpinionCelebrating click chemistry’s 25th birthday
The field ‘is nowhere near mature – if not in its infancy, then perhaps enjoying a highly active childhood’, says one of click chemistry’s orignators
-
OpinionWhy I think it’s time to change how we teach the inductive effect
New evidence challenges the idea of long‑range inductive transmission, highlighting that some textbook explanations of inductive effects are oversimplified and, in key cases, completely wrong
-
-
Research25 years ago click chemistry changed science. What happened next?
Barry Sharpless and his team first introduced the concept of ‘clicking’ molecules together 25 years ago
-
OpinionClick chemistry, 25 years on
A quarter of a century since first introducing the concpet of ‘click’, one of its originators explains how it became a transformational tool for scientists
-
ResearchStudy points to ammonia contamination in water microdroplets saga
Replication effort attributes mass spectrometry peaks to ammonium not hydroxyl species
-
ResearchElusive electronic effect could explain the origins of chirality for all life on Earth
Study suggests spin selectivity is different in enantiomers – altering their reaction rate – which ‘challenges a fundamental assumption in the field’
-
ResearchElectrifying MOF synthesis drastically reduces time it takes to make them
External electric fields stimulate the formation of various metal–organic framework materials
-
Research‘Flip-over’ nucleophilic substitution reaction challenges classic SN2 textbook mechanism
Team behind work say this is a reminder that even simple reactions are more complicated than they first seem
-
ResearchClick chemistry toolbox expanded with 'forbidden' C–C bond forming reaction
Copper-catalysed addition produces functional links that should be compatible with biological systems
-
ResearchVersatile skeletal editing strategies upgrade nitrogen compounds into drug building blocks
Two techniques could help speed up the discovery of drugs containing nitrogen heterocycles
-
ResearchSilver bullet catalyst works magic transforming stable C–H bonds into amines
Method allows for late-stage, stereoselective aminations to drug-like molecules