All Organic chemistry articles
View all stories with this category.
-
ResearchNew silicon-based protecting group removable with blue light
Benzoyldiisopropylchlorosilane protects primary, secondary and tertiary alcohols, and also works alongside other protecting groups
-
FeatureReaching into the non-covalent toolbox
Alongside supramolecular stalwarts, budding bonding forms are vying to be valuable, finds Andy Extance
-
FeatureThe mechanical side of bonding
Synthetic chemists are finally mastering the assembly of interlocked molecules held together by the mechanical bond, find James Mitchell Crow
-
NewsFuture House wants to build an AI biologist. They’re looking to a chemistry LLM for inspiration
ChemCrow has already recorded success researching, designing and producing an insecticide on its own
-
ResearchSkeletal editing that simply swaps aromatic carbons for nitrogens will aid drug discovery
Atom-swapping chemistry gains two new techniques that are ready to use
-
OpinionSlow march of the retrosynthesis robots
Software synthesis suggestions are hampered by biased and incomplete datasets
-
ResearchElusive crystals provide structural evidence of global aromaticity in a macrocyclic hydrocarbon
Reduced forms of [24]paracyclophanetetraene provide fresh understanding of redox-based aromaticity switching
-
ResearchActivating a chemical reaction by ‘flipping a switch’
A low-cost microfluidic reactor could cut the environmental footprint of synthesis by directing electrons via an external electric field
-
ResearchSimple substitution creates subset of rhodamine fluorophores with extreme solubility
Tetramethyl-substituted 3-phosphonorhodamines look set to find use in cellular imaging
-
ResearchElectrophilic aromatic bromination study casts doubt on textbook intermediate
New computational evidence that electrophilic aromatic bromination actually occurs via an addition–elimination mechanism
-
ResearchMOFs offer safer solution for handling fluorinated gases that can ‘tame the tiger’
Compounds vital in medicinal chemistry and imaging can be stored ready to use at room temperature
-
ResearchDoubly oxidised carbene tests the limits of the octet rule
Removal of two non-bonding electrons creates four-electron intermediate that could find use in synthesis
-
Opinion(+)-iso-Phomopsene (and friends)
A non-obvious combination unleashes the power of electrocyclisation
-
ResearchTransformation analysis reveals structural similarities in FDA-approved drugs
Reaction informatics tools combined to create a new method for mapping chemical space
-
Research‘Transformative’ carbonyl cross-metathesis used to synthesise alkenes
Two new catalytic methods can produce a broad range of Z- and E-alkenes with remarkable cross-selectivity, paving the way for more efficient organic syntheses
-
ResearchElectrochemical conversion of acids to alkenes achieved on kilogram scale
Efficient production of valuable alkenes achieved under mild conditions by reversing hydrocarboxylation reaction
-
ResearchChemical oscillator’s tick-tock action catalyses reaction regular as clockwork
Small molecule oscillator can catalyse Knoevenagel condensation periodically without affecting the oscillation
-
ResearchClever ligand design enables alcohol-directed C-H activation
Despite being the most common functional group in nature alcohols have proven difficult to functionalise
-
WebinarAntimicrobial resistance: Exploring the One Health perspective and wastewater monitoring
The challenges created by antimicrobial resistance are only set to grow. Join us to equip yourself with the most up-to-date facts and knowledge
-
ResearchCopper catalyst behind general strategy for synthesising methylenecyclobutane compounds
Simple method that produces strained and synthetically-demanding molecules could be a boon for medicinal chemists