All Organic chemistry articles
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ResearchSimple way to construct molecules with perfluoroalkyl bridges
Troublesome side reaction becomes useful synthetic tool
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Opinion
Cleaning up chemical kitchens
In a busy plant, ensuring small changes don’t produce unforeseen toxic impurities is key
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Research
Flow synthesis produces chiral intermediate for antidepressant drug
The first solvent-free organocatalytic flow process yields the key chiral intermediate for paroxetine on a multigram-scale
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Research
Total synthesis of unnatural enantiomer renews interest in quinine
Scientists hope their strategy will invigorate cinchona alkaloid-mimic catalysis
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Research
Chemists taken aback as dinitrogen found to speed up some reactions
Warnings that nitrogen should no longer be considered just an inert carrier gas
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Research
Biomimetic synthesis cultivates yellow poppy pigment
Cascade process that fuses indole with orientalin verifies biosynthesis of nudicaulins
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Research
Steric shield leads boron to aromatic rings’ most remote region
Bulky blocking counterion makes quick work of borylating arenes’ inaccessible para position
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Opinion
(±)-Rhabdastrellic acid A
A triterpene that looks innocuous until it reveals the highly strained conformation of its rings
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Research
Light intensity changes can switch photocatalyst between one- and two-photon mechanisms
Simple optical lens behind strategy for manipulating photochemical reactivity
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Research
Lignin and carbon dioxide turned into ethanol
Process generates bulk chemical from two renewable carbon sources
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Research
Mystery of whether or not kekulene is superaromatic unravelled after 41 years
Second-ever synthesis and first atomic resolution images of superbenzene reveal its electronic nature
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Research
Carbynes expand the possibilities of carbon–carbon double bonds
Chemists use novel monovalent carbon species to insert functionalities in the middle of double bonds
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Research
Alzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
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Research
Synthetic flame retardant compounds turn up as marine natural products
Finding an alga that biosynthesises halogenated anilines increases likelihood of finding an organism that can degrade the toxic compounds too
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Opinion
Stille cross-coupling
Palladium and tin combined to lay the foundations for a revolution in C–C bond-forming reactions
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Research
Template molecules round-up extra-large cyclodextrins from enzymatic synthesis
Scientists rethink how they use enzymes in chemical synthesis by exerting thermodynamic, rather than kinetic, control
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Research
Universal method bypasses obstacles to making neglected hydrocarbon skeletons
Universal method bypasses obstacles to making neglected hydrocarbon skeletons
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Opinion
Embracing structural disorder
Medicinal chemists need to overcome their fear of fuzzy proteins
