All Organic chemistry articles
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FeatureHow organocatalysis won the Nobel prize
Jamie Durrani tells the story of how two young upstarts, Ben List and David MacMillan, created a whole new field of catalysis
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Research
Exploiting evolution to explore chemical space shows promise for drug discovery
Using molecular trees – similar to family trees – chemists could predict how products will evolve to make new molecules
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Research
Möbius metallacycles show their aromaticity with textbook reactivity
First electrophilic aromatic substitution reactions with unusual molecules
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Research
Explainer: why has asymmetric organocatalysis won the chemistry Nobel prize?
In a rather unexpected move by the Nobel committee, this year’s prize in chemistry has been awarded to Benjamin List and David MacMillan
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News
Asymmetric organocatalysis scoops 2021 chemistry Nobel prize
Benjamin List and David MacMillan recognised for research that makes chemistry greener
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Research
Peptide superstructures speed up Michael reaction
A tripeptide that self-assembles into a supramolecular fibres accelerates an asymmetric benchmark reaction by up to 74%
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Research
Ultraphosphates break decades-old anti-branching rule
Discovery of elusive branched phosphates’ unexpected stability means they could have played a role in prebiotic chemistry
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Research
Method to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
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Research
Enantioselective synthesis of elusive chiral nitrogen compounds discovered by chance
An ‘elegant and simple’ way to make nitrogen stereocentres by supramolecular recognition
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Research
Blue light squeezes out heteroatoms from small rings
Photochemical ring editing reaction allows complete molecular shape change in a single step
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Research
No more worrying about nomenclature – AI will tell you what that chemical is called
Open-source online resource converts organic chemical structures to their Iupac names and vice versa
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Research
App creates floating 3D molecules from hand-drawn chemical structures
MolAR also lets users visualise molecules in water, coffee and fruit by scanning them with a smartphone camera
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Research
Gold(III) catalysis transforms protecting group from base-stable to base-labile
Unique orthogonality in a protecting group achieved using a gold-catalysed cyclisation for selective activation and deprotection
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Research
Safer fluorination process developed using flow electrochemistry
Automated system for constructing carbon–fluorine bonds quenches fluorine compounds to reduce exposure and risk to lab chemists
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Feature
The search for the grand unification of aromaticity
Researchers have been trying to find a full definition of aromaticity for almost two centuries, and yet keep discovering new types
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Research
Newly discovered marine compound is in a super-carbon-chain league of its own
Isolated from algae, Benthol A has 35 stereocentres
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Research
Molecular light switch speeds up tricky cyclodextrin synthesis
Reaction could lower cost of useful macrocycle
