Organic chemistry
The latest chemistry news and research on organic chemistry, including synthesis, natural products and total synthesis, reaction mechanisms and supramolecular chemistry, from the Royal Society of Chemistry's magazine, Chemistry World
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ResearchStrange tetra-alcohol synthesised in simulated interstellar ice
After finding ‘impossible molecule’ methanetriol, team reaches ‘the final frontier’ and detects methanetetrol after 100 years
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ResearchClever carbene chemistry offers unified way to make cyclopropanes
Radical route cuts out explosive reagents
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ResearchCarbene coating completely cuts corrosion on iron surfaces
A ’molecular double-sided tape’ protects iron from rusting with 99.6% efficiency
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ResearchMorphine analogues kill pain with fewer negative side effects
Redesign of the potent painkiller’s core prevents breathing suppression and reduces addiction-related behaviours in mice
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ResearchBoron building block assembles tetra-substituted alkenes like Lego
Powerful method offers control of stereochemistry to produce drugs and natural products
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ResearchSilicon-based ‘ladder molecules’ take a step up in complexity
New compounds are ‘among the most complex organosilanes ever synthesised’
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ResearchSeventy-year search for simpler route to valuable reactive intermediate ends
Ortho-quinodimethane made under mild conditions from common reagents
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OpinionGetting good at human tasks
’What do you mean you had to lock the NMR with an oscilloscope and shim the magnet by hand?’
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Research‘Microlightning’ released by peeling tape can drive chemical reactions
Intense localised electric fields can break bonds
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ResearchPath to carbon dioxide-based chemicals smoothed with a dash of acid
Hydrochloric acid dissolves salts that gum-up reaction process
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ResearchWhy some sunscreens turn clothes crimson when bleached
Laundry mishap leads researchers to a surprising substitution reaction
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OpinionContemporary chemistry owes a lot to benzene's beginnings
Celebrating what started when Faraday found the molecule with no end
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NewsHow to find out if your magnetic stirrer is affecting your results – and how to fix it
Valentine Ananikov explains how the humble stirrer bar may be altering your results
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ResearchSuper-reducing photoredox catalyst paves a new way for arene reduction
Bio-inspired catalyst can reduce arenes without the need for harsh conditions
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ResearchAbundant alkanes become gaseous alkylating agent with flow chemistry
Photocatalytic process can carry out late-stage optimisation of drug candidates
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ResearchLotions and perfumes found to affect ‘human oxidation field’ chemistry
What this means for us, if anything, is still unclear
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ResearchWinery cuts costs with carbon capture pilot plant that uses metal–organic framework
Carbon dioxide captured from fermentation in a scalable, selective and sustainable manner
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OpinionNormalising huge substrate scopes worsens wellbeing
And holds up the pace of scientific progress
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ResearchSelective C–H bond fluorination enables conformational reporting in a complex natural product
Radical fluorination leaves extant functional groups intact