Drug discovery and development – Page 32
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FeatureMapping the mosquito
Uncovering how mosquitoes sniff out their human victims may lead to new tools to conquer malaria and dengue fever. Emma Davies reports
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ResearchNew antibiotic could treat infection while dodging resistance problems
Technique to tap huge unexplored reservoir of natural products in soil microorganisms finds promising compound
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BusinessMerck & Co to buy antibiotics specialist Cubist
Pharma giant remains committed to $9.5bn deal despite key Cubist patents being invalidated by court ruling
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News
Tufts’ $2.6bn drug development figure questioned
Details sought about how university determined cost of bringing a drug to market jumped 145% since 2003
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NewsEbola vaccine passes first safety hurdle
Researchers hope to begin larger trials of its effectiveness in west Africa soon
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OpinionProgress at the pace of the slowest
Chemistry is rarely the rate-limiting process in getting a drug to market, says Derek Lowe
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News
US drug development costs surge
The price of developing new prescription drugs in the US has increased 145% since 2003, Tufts data shows
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NewsUS agency fast-tracks Ebola vaccine development
Health and Human Services invests almost $6 million to ready an Ebola vaccine candidate for clinical trials, meanwhile GSK says its vaccine is progressing at an ‘unprecedented rate’
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Business
Actavis boosts antibiotics with Durata buyout
$820 million deal gives Actavis control of newly-approved intravenous antibiotic
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FeaturePepping up antibiotics
Industry and academia are turning to antimicrobial peptides to find new antibiotics, Andy Extance discovers
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FeatureChemistry in bloom
Sarah Houlton discovers the chemistry among the specimens at many botanical gardens
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ResearchCoated nanoparticles show Alzheimer's promise
Gold nanoparticles functionalised with amino acid polymer inhibit the growth of amyloid fibres associated with neurodegenerative disease
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ResearchAntimalarial flow synthesis closer to commercialisation
Scientists in Germany hope their continuous flow method will boost accessibility of artemisinin-derived medicines
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ResearchBringing chemical synthesis to the masses
Researchers hope simple system to build thousands of peptides without enzymes, cells or reagents will be accessible to all
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Business
Piramal exits drug discovery in India
Company will concentrate on generic medicines and clinical and contract research.
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ResearchFluorinating new life into an increasingly ineffective antibiotic
Aminoglycoside analogue evades bacterial resistance mechanism
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Research
Ionic liquids join battle against antibiotic resistance
Organic salts disrupt biofilms to leave resistant bacteria at the mercy of antibiotics