Drug discovery and development – Page 28
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BusinessSanofi and Merck & Co end vaccines partnership
Two-decade-long alliance will split by end of 2016
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NewsThe huge impact of ‘mini-brains’
‘Mini-brains’ created by Johns Hopkins researchers in the US could revolutionise how drugs and compounds are tested for safety and effectiveness
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News‘Map’ of chemical landscape could cut animal testing
Searchable database of 10,000 chemicals could help to create safety profiles for untested compounds
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PodcastFlibanserin
Flibanserin was touted to be the female Viagra. Martha Henriques explains why it failed to live up to the hype.
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NewsAntibiotic alternatives need to be recruited in fight against resistance
Vaccines, probiotics and other substitutes could help battle antimicrobial resistance as antibiotic effectiveness fades
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FeatureAge of the phage
Hayley Birch discovers how researchers are using proteins from viruses to create new antimicrobial drugs
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ResearchBoost for non-animal toxicology testing
Thousands of compounds have been screened in a bid to develop in vitro toxicity tests
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OpinionThe kids aren’t alright
Making it more attractive for companies to develop paediatric drugs has the potential to improve everyone’s lives
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BusinessClinical trial death highlights hazards
Pain drug trial has left one dead and five hospitalised in France, with little indication as to the cause of the problems
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ResearchDrug labelling problems ironed out by new catalyst
Cost-effective method to tritiate compounds offers way to track drug metabolism while minimising radioactive waste
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ResearchEasy addition of ‘unnatural’ strained rings boon for drug chemists
Technique can slow metabolism of medicines, giving them more time to work
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BusinessFixing the broken antibiotics business model
With rising resistance and doomsday warnings, focus is turning to alternative economic models to boost antibiotic R&D
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Business
Mexico approves world’s first dengue vaccine
Sanofi’s vaccine protects children and adults against the mosquito-borne disease
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Business
BioAtla and Pfizer to collaborate on antibody research
Two-way agreement to share technology and royalties on new cancer drugs
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Business
Heptares takes on new partners for drug discovery
Firm set to receive over $1bn from research partnerships
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NewsReview calls for tighter controls on antibiotic use in farming
Legally binding targets are needed to tackle resistance worldwide, latest report says
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Business
Drug firms to share chemical compound libraries
AstraZeneca and Sanofi aim to facilitate drug discovery by swapping 210,000 proprietary chemical compounds