Drug discovery and development – Page 28
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ResearchMolecular structure is teixobactin’s pièce de résistance
Study builds scientists’ arsenal against drug-resistant superbugs
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NewsAlzheimer’s disease: have drug developers been on the wrong track?
Dementia drug developers urged to look beyond amyloid
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NewsVaccine coalition to target emerging infectious diseases
Fund attempting to raise $1 billion to develop vaccines before an epidemic strikes
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BusinessTaming vaccines with chemistry
Vaxxilon aims to simplify vaccine development by replacing biological components with well-defined synthetic molecules
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FeatureNew opioid drugs
Creating powerful new painkillers is a constant battle against side-effects – particularly addictions. James Mitchell Crow reports
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OpinionHow much does fashion influence chemists?
Is that new reaction the next Nobel-worthy breakthrough, or just a flash in the pan?
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OpinionRestarting the mental health pipeline
The lack of UK investment in new drugs for mental health disorders is a problem – but the tide may be about to turn
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CareersThe trials and tribulations of drug discovery
The many pitfalls medicinal chemists face when creating a new drug
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ResearchDibrominated tag helps identify new natural products
New substance allows researchers to find new aldehyde- and ketone-containing natural products
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OpinionRegulatory tightropes
When lobbying and marketing clash with scientific evidence, regulators walk a fine line
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OpinionPutting chemistry back in biology
The chemical nature of biomolecular interactions can no longer be ignored
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BusinessLilly to buy Boehringer’s pet vaccines
Deal strengthens Lilly’s animal medicine division following recent acquisition
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FeatureDrugging the epigenome
Drugs that change how your genes are switched on or off could change how we treat many diseases, as Rachel Brazil discovers
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NewsPharma giants commit to tackling antimicrobial resistance
Plan to tackle superbugs includes changes to manufacturing and sales incentives
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ResearchFreeze-dried cell parts for hassle-free molecule manufacturing
‘Just add water’ reaction pellets allow drugs and vaccines to be produced without special equipment or training
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OpinionSlimmer synthesis
Atom economy is a noble aim, but there are other routes to efficient molecule making
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BusinessFDA’s first Duchenne drug approval reveals schism
Oligonucleotide drug reaches market amid pressure from patient families and strife over ‘patient-focused drug development’ at the regulator
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ResearchSynthesis strategy takes the pain out of finding malaria drugs
Compound libraries could help find treatments for a whole host of diseases