Drug discovery and development – Page 27
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OpinionPutting chemistry back in biology
The chemical nature of biomolecular interactions can no longer be ignored
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BusinessLilly to buy Boehringer’s pet vaccines
Deal strengthens Lilly’s animal medicine division following recent acquisition
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FeatureDrugging the epigenome
Drugs that change how your genes are switched on or off could change how we treat many diseases, as Rachel Brazil discovers
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NewsPharma giants commit to tackling antimicrobial resistance
Plan to tackle superbugs includes changes to manufacturing and sales incentives
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ResearchFreeze-dried cell parts for hassle-free molecule manufacturing
‘Just add water’ reaction pellets allow drugs and vaccines to be produced without special equipment or training
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OpinionSlimmer synthesis
Atom economy is a noble aim, but there are other routes to efficient molecule making
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BusinessFDA’s first Duchenne drug approval reveals schism
Oligonucleotide drug reaches market amid pressure from patient families and strife over ‘patient-focused drug development’ at the regulator
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ResearchSynthesis strategy takes the pain out of finding malaria drugs
Compound libraries could help find treatments for a whole host of diseases
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BusinessJoined-up thinking
The rift between contract medicinal chemistry and chemical development needs to be bridged
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OpinionDon’t fear the Crispr
Does simple gene-editing mean the end of traditional medicinal chemistry? Probably not
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BusinessPfizer to buy Astrazeneca’s antibiotics
Deal tops up Pfizer’s late-stage development pipeline, but AZ will retain biological programmes
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OpinionHow to solve global health inequality
Our skills as scientists hold the answer, says the Bill & Melinda Gates Foundation
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OpinionPreparing for the future of pharma
Dave Allen discusses how scenario planning helps to define uncertainty in pharma
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NewsAntibiotic partnership plans accelerated drug development
Public–private venture will invest $350 million over five years but there are warnings that much more money is still needed
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ResearchNew antibiotic picked from nose bacteria
Discovery suggests human microbiome may be an untapped source of antimicrobial compounds
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ResearchGold nanoclusters offer route to better vaccines
New technique improves immune response and safety of hepatitis E vaccine
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PodcastThiomersal
Kat Arney introduces the organomercury preservative associated with the current controversy around vaccines
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OpinionWe need a global plan to beat resistance
We all need to do our bit and act for the common good if we’re going to protect antibiotics
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OpinionLinked data is the future for medicinal chemistry
Paul Groth explains why linked data is starting to revolutionise medicinal chemistry