Drug discovery and development – Page 29
-
OpinionSlimmer synthesis
Atom economy is a noble aim, but there are other routes to efficient molecule making
-
BusinessFDA’s first Duchenne drug approval reveals schism
Oligonucleotide drug reaches market amid pressure from patient families and strife over ‘patient-focused drug development’ at the regulator
-
ResearchSynthesis strategy takes the pain out of finding malaria drugs
Compound libraries could help find treatments for a whole host of diseases
-
BusinessJoined-up thinking
The rift between contract medicinal chemistry and chemical development needs to be bridged
-
OpinionDon’t fear the Crispr
Does simple gene-editing mean the end of traditional medicinal chemistry? Probably not
-
BusinessPfizer to buy Astrazeneca’s antibiotics
Deal tops up Pfizer’s late-stage development pipeline, but AZ will retain biological programmes
-
OpinionHow to solve global health inequality
Our skills as scientists hold the answer, says the Bill & Melinda Gates Foundation
-
OpinionPreparing for the future of pharma
Dave Allen discusses how scenario planning helps to define uncertainty in pharma
-
-
NewsAntibiotic partnership plans accelerated drug development
Public–private venture will invest $350 million over five years but there are warnings that much more money is still needed
-
ResearchNew antibiotic picked from nose bacteria
Discovery suggests human microbiome may be an untapped source of antimicrobial compounds
-
ResearchGold nanoclusters offer route to better vaccines
New technique improves immune response and safety of hepatitis E vaccine
-
PodcastThiomersal
Kat Arney introduces the organomercury preservative associated with the current controversy around vaccines
-
OpinionWe need a global plan to beat resistance
We all need to do our bit and act for the common good if we’re going to protect antibiotics
-
OpinionLinked data is the future for medicinal chemistry
Paul Groth explains why linked data is starting to revolutionise medicinal chemistry
-
Feature2Heavy drugs gaining momentum
With the first approval of a drug containing deuterium looking imminent, Nina Notman surveys the deuterated drug landscape
-
ResearchMirror-image trick yields real hits from a virtual chemical library
Scientists use mirror-image protein to identify potential new drugs from a previously unexplored library of natural product enantiomers
-
NewsWorld faces tough challenge turning words into action on antibiotic resistance
Countries are waking up to the challenge of ‘superbugs’ but agreeing a way forward will be tricky
-
ResearchChemical synthesis injects new life into old antibiotics
Approach can construct wide range of new antibiotic candidates from simple chemical building blocks
-
News
Large HIV vaccine trial to launch in South Africa
US funding agency will enlist 5400 people for HIV vaccine study in South Africa in November