Drug discovery and development – Page 30
-
News
Scientist imprisoned over fraudulent HIV vaccine research
Former Iowa State University researcher gets four-and-a-half years in prison for faking vaccine research funded by the NIH
-
FeatureOrganic odysseys
Andy Extance looks at two drugs that cranked the synthetic challenge all the way up to Halaven
-
News
NIH plan to get drug development unit back online
The US National Institutes of Health to address deficiencies in unit that makes drugs for research studies
-
News
Crowdsourcing compounds to tackle antibiotic resistance
A global screening project is searching for new antibiotics by asking chemists to send in novel compounds
-
ResearchPromising compound offers single dose knock-out for malaria
Candidate antimalarial drug halt parasite protein synthesis and will enter human trials in a year
-
ResearchRegulators have drug firms chasing phantom impurity
Mutagenic contaminants that supposedly form in sulfonic acid salts are highly unlikely to arise
-
News
US spends billions annually on unreproducible preclinical research
Study estimates $28 billion spent yearly on preclinical research that can’t be replicated
-
-
OpinionMagic molecule modifiers
Late stage functionalisation can seem supernaturally powerful, says Derek Lowe – if you’ve got the nerve to try it
-
ResearchTaking the lead on drug discovery
Making compounds that promise to become useful drugs has just become a little easier
-
NewsRoadmap to reward pharma for creating new antibiotics unveiled
Report recommends large up-front payments and an innovation fund for blue skies research to tackle microbial resistance
-
ReviewVenoms to drugs: venom as a source for the development of human therapeutics
Defanging chemistry
-
ResearchZombie cells may rise up to kill infections
Bacteria killed by silver may act as vessels for the metal to kill other pathogens
-
ResearchSiRNA treatment cures Ebola in monkeys
Researchers perform the first successful trial for a drug against the current strain of Ebola
-
FeatureCombating rare diseases
Developing drugs for treating rare diseases isn’t always financially viable. Clare Sansom looks at some recent success stories
-
Opinion'What gets measured gets done'
Measuring R&D productivity is a thorny issue. Dennis Lendrem urges the pharmaceutical industry to learn from its mistakes.
-
OpinionAnalogues by catalogue
Buying in screening compounds directly feels like cutting out the synthetic chemist middleman, says Derek Lowe
-
Business23andMe jumps into drug R&D
Gene profiling firm aims to capitalise on its databank of genetic information to discover new drugs
-
