Drug discovery and development – Page 30
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Opinion
A shot in the arm
Vaccines for diseases that afflict the world’s poorest offer an escape not only from disease but also from poverty
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PodcastChemistry World podcast – September 2015
In this months podcast, we discuss Ebola and malaria vaccines in the pipeline, the history of peer review, and managing the mountain of chemical data
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BusinessNo one should be denied medication
Exclusive interview with Yusuf Hamied, chairman of Indian generic drugmaker Cipla
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ResearchBee immune system discovery points way to pollinator 'vaccines'
Molecular mechanism in the bee immune system could save populations in decline
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NewsVaccine raises hopes of an end to Ebola
Trial shows vaccine provides complete protection and points way to fast-tracking medical research
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PodcastChemistry World podcast – August 2015
In this space special, we learn how to study comets surfaces, and speak to a Nobel Prize winner about his 20-year-old prediction proving to be correct
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NewsMalaria vaccine approval first marred by efficacy question mark
Low protection rates in trials and uncertainty over cost-effectiveness leave vaccine’s future up in the air
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News
Scientist imprisoned over fraudulent HIV vaccine research
Former Iowa State University researcher gets four-and-a-half years in prison for faking vaccine research funded by the NIH
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FeatureOrganic odysseys
Andy Extance looks at two drugs that cranked the synthetic challenge all the way up to Halaven
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News
NIH plan to get drug development unit back online
The US National Institutes of Health to address deficiencies in unit that makes drugs for research studies
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News
Crowdsourcing compounds to tackle antibiotic resistance
A global screening project is searching for new antibiotics by asking chemists to send in novel compounds
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ResearchPromising compound offers single dose knock-out for malaria
Candidate antimalarial drug halt parasite protein synthesis and will enter human trials in a year
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ResearchRegulators have drug firms chasing phantom impurity
Mutagenic contaminants that supposedly form in sulfonic acid salts are highly unlikely to arise
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News
US spends billions annually on unreproducible preclinical research
Study estimates $28 billion spent yearly on preclinical research that can’t be replicated
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OpinionMagic molecule modifiers
Late stage functionalisation can seem supernaturally powerful, says Derek Lowe – if you’ve got the nerve to try it
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ResearchTaking the lead on drug discovery
Making compounds that promise to become useful drugs has just become a little easier
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NewsRoadmap to reward pharma for creating new antibiotics unveiled
Report recommends large up-front payments and an innovation fund for blue skies research to tackle microbial resistance
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ReviewVenoms to drugs: venom as a source for the development of human therapeutics
Defanging chemistry