Pharmaceutical industry – Page 24
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Business
Mylan settles Epipen overcharging allegations
Company will pay US Department of Justice $465m for avoiding paying rebates to government healthcare systems
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Opinion
Make room for randomness in drug development
Setting free the dark horses sometimes beats the most rational planning
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Business
Chemical and pharma bosses quit US manufacturing council
President Trump disbands the group after multiple advisers resign in protest against his stance on racism
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Webinar
Current topics in bioconjugation
Insights into making bioconjugates using optimal reagents and the latest techniques to create highly active and stable complexes
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Feature
Environmentally benign by design
The challenge of designing drugs with biodegradability in mind
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Business
US court denies Amgen appeal over Pfizer biosimilar
Amgen has lost its bid to compel Pfizer to divulge information about its version of anaemia drug Epogen
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Business
Roche offloads majority of rights to lebrikizumab
Deal with Dermira could be worth well over $1 billion
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Business
GSK stops over 30 research programmes to prioritise innovation
New boss Emma Walmsley outlines sweeping changes in order to focus on high-return drug projects
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Business
AstraZeneca shares tumble after antibody failure
Imfinzi and tremelimumab checkpoint inhibitor pairing fails to beat chemotherapy in lung cancer
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Business
Novartis coasts towards first CAR-T approval
Unanimous recommendation for CTL019 ahead of October decision builds confidence in T-cell genetic reprogramming
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Opinion
(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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Business
Broad Institute backs central Crispr patent licensing platform
Key players submit 22 patents to pool, and urge other holders to create a one-stop shop for licensing deals
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Business
Lilly wins chemotherapy patent appeal
Firm also settles with generic manufacturers of erectile dysfunction drug Cialis
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Business
Mallinckrodt settles US opioid lawsuit
Firm will pay $35m over allegations it failed to report suspicious orders of controlled substances
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Opinion
Making enough of a difference
What if the needle in the drug development haystack ends up being too small to be useful?
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Business
FDA approves first sickle cell drug in almost two decades
Glutamine-based drug is the first approved for children over 5
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Business
Celgene and BeiGene agree cancer partnership
Immuno-oncology deal sees firms exchange licensing rights for antibody drugs
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Business
Silence Therapeutics and Alnylam in patent dispute
Suit alleges competitors need to license Silence patents relating to their drug cantidates
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Business
Amplifying intelligent drug design
This year’s Chemistry World Entrepreneur of the year is Andrew Hopkins of start-up Exscientia and the University of Dundee, UK
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Research
Lilly pushes continuous drug production limits
Integrated flow synthesis and purification process for prexasertib meets high industry standards