Pharmacology and psychoactive substances – Page 2
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OpinionThe side effects of being unique
Even the largest clinical trials won’t capture all possible bad reactions to a drug – we need pharmacovigilance
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BusinessAntibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
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ResearchPeptides self-assemble to support growth of artificial tumours
Cancer cells grown around bioengineered microfibres make an ideal model to test new chemotherapy drugs
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NewsCaution urged as scientists await results of trial that finds steroid cuts Covid-19 deaths
Claims that 60-year-old drug dexamethasone dramatically lowers fatality rate of seriously ill Covid-19 patients await peer review
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ResearchMethod that yields oxygen-18-enriched alcohols set to bolster drug studies
Mitsunobu-based protocol is simple alternative to limited and lengthy methods
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ResearchDatabase offers another way to search for drugs – by activity not structure
Dataset offers new way for biomedical researchers to identify potential drug candidates
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PodcastInterferon beta
An immune-modulating compound used to reduce the symptoms of multiple sclerosis and now showing potential against coronaviruses
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NewsScience steps up a gear as struggle to both understand and fight coronavirus intensifies
Research that might have taken years is being turned around in months as journals fast-track Covid-19 manuscripts
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ResearchAI tool screens 107 million molecules, discovers potent new antibiotics
Deep learning approach could help in fight against drug-resistant bacteria
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OpinionTwo heads are better than one
Bifunctionals show that sometimes simply tethering two useful molecules together unlocks some useful activity
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NewsPoor antibiotic stewardship blamed as India found to be superbug’s birthplace
Spread of superbugs a growing problem for the subcontinent
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Podcast2C psychedelics
A class of hallucinogenic phenethylamines, explored by the 'godfather of psychedelics' Alexander Shulgin and sadly implicated in a tragedy at a 2017 music festival
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PodcastAmantadine
Katrina Krämer investigates how one of the smallest small molecule drugs around saved Jeanna Giese's life
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ResearchTrefoil knots steer cancer drug leads in fresh direction
Chemists look to links and knots in the search for new cancer therapies
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PodcastMethylphenidate (Ritalin)
Jamie Durrani diverts his attention to the rise of Ritalin, a drug first identified as a way of improving tennis performance
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ArticleHow biologics have changed the rules for pharma
The impact of the latest generation of drugs for the healthcare industry
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PodcastLimulus Amebocyte Lysate
Frances Addison takes a look at the discovery that brought horseshoe crabs to the heart of the pharmaceutical industry