All Reactions and synthesis articles – Page 30
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Research
Crowdsourced drug discovery pits half-forgotten compounds against neglected diseases
45 research groups donate 350 compounds to the first crowdsourced screening library
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Research
Benzene transformed into nanotubes with predictable defects
Synthesis delivers molecular cylinders that contain 240 sp2-carbon atoms
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Research
Lightning-inspired method makes ammonia with no catalyst
Plasma-enabled electrolysis produces the vital gas in high purity – but also consumes much more energy than current methods
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Research
Enzyme evolved that can perform reactions new to nature
New possibilities for organic synthesis with enzymatic C–H functionalisation
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Research
Blood pressure drug reacts with membrane lipids
Lipidation products add to evidence that biological membranes are far from chemically inert
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Opinion
Chiral curiosities
The challenges posed by asymmetry go hand in hand with fascinating insights into developmental biology
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Research
New tools direct reactions at specific C–H bonds in organic molecules
Elegant catalysts offer quicker routes to complex compounds
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Research
Catalytically, is copper the new gold?
Approach for depositing copper on silica support influences how easily it oxidises, and in turn the reactions it catalyses
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Business
How many papers do you read a week?
Everyone needs a strategy to keep up with the literature
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Research
Dispute over reaction prediction puts machine learning’s pitfalls in spotlight
Two research teams’ argument over a reaction-predicting algorithm show that there is still a lot to understand when applying machine learning to chemistry
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Feature
Science in microgravity
How does gravity affect chemistry and biology? More than you might think – and you don’t have to visit space to find out, as Rachel Brazil discovers
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Research
Foam catalyst performs hydrogen evolution in neutral conditions
Structure decouples water dissociation and hydrogen evolution processes
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Research
Light catalyst breaks mirror symmetry in first reverse racemisation
Transformation makes single mirror image molecules in a ‘completely different way of doing enantioselective chemistry’
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Research
Catalyst predictor shows drug manufacturing promise
Joint industrial–academic team develops and validates force-field tool for identifying ligands for enantioselective catalysis
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Research
Weird mechanism behind catnip compound’s biosynthesis uncovered
Nepetalactone – the compound cats go crazy for – is made by a two-step procedure that is unlike any other in terpenoid biosynthesis
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Research
Crop rotation for catalysts
Chemists take a leaf out of agriculture books to devise method for extending catalyst lifetime
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Podcast
Low-background steel
Post-nuclear steel is a little bit radioactive, so for some specialist jobs we need to find a source of steel from before the bomb
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Research
Double umpolung approach to amino amide synthesis
Unusual disconnection strategy behind stereocontrolled route to β-amino amides
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Research
Erythropoietin benefits from controlled sugar-coating
Click chemistry allows glycosylation at virtually any synthetic stage
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Research
Robotic organic synthesis to make reproducibility simple in chemistry
Chemputer claims universality after making three drugs without human intervention