Antibiotics – Page 3
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ResearchGenentech antibiotic quells resistance
Modified arylomycin combines high potency with new mechanism of action
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ResearchBismuth drugs kill bacteria by disrupting metabolism
Scientists throw kitchen sink of omics techniques at understanding complicated response of prevalent human pathogen to bismuth drug
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BusinessNovartis exit from antibiotics a setback for race against resistance
Experts say business models must change to halt big pharma exodus
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NewsWhy antibiotic pollution is a global threat
Rising antibiotic resistance caused by pollutants needs action
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OpinionWhy combination pills aren’t always the answer
The challenges of medicines containing multiple drugs aren’t going away
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NewsIllegal antibiotic combinations threaten efforts to battle antimicrobial resistance
Unapproved formulations make up two-thirds of combination therapies sold in India
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ResearchAntibiotic analogue puts researchers on path to ending herbicide drought
Research flags DNA gyrase as a new target for pesticides
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ResearchSoil search unearths new class of antibiotics
Malacidins have a novel mode of action and can kill MRSA
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ResearchSingle-cell imaging spots resistant infections in less than half an hour
Microfluidic device allows speedy susceptibility testing so the right antibiotic can be given
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ResearchStructural sleuthing salvages superbug slayer
Combining ‘assembly line’ synthesis, spectroscopy and computational predictions solves stereochemistry riddle
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ResearchPlotting a course to new antibiotics
Mapping out the chemical space of peptide antibiotics offers an efficient way to find new compounds
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Opinion(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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ResearchSimplified structure eases antibiotic synthesis
New analogues of the potent antibiotic teixobactin could be instrumental in the fight against multi-drug resistant pathogens
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NewsEuropean ‘One Health’ plan aims to curb antimicrobial resistance
Action plan treats human and animal health as interconnected
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ResearchModified antibiotic beats superbug resistance
Adding functional groups to vancomycin gives it extra modes of attack against resistant bacteria
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BusinessPollution from Indian drugmakers drives drug resistance
Areas around manufacturing sites still heavily contaminated with antimicrobials and breeding multidrug-resistant pathogens
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ResearchHow total synthesis is creating antibiotics
Macrolide synthesis could reinvigorate the antibiotic pipeline
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ResearchMaple syrup enhances antibiotics
A phenol-rich mixture extracted from maple syrup allows much smaller doses of antibacterial drugs to achieve the same results
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ResearchPutting the ‘ant’ in antibiotics
Antibacterial polyketides uncovered in the most unusual of places