Antibiotics – Page 4
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ResearchPlotting a course to new antibiotics
Mapping out the chemical space of peptide antibiotics offers an efficient way to find new compounds
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Opinion(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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ResearchSimplified structure eases antibiotic synthesis
New analogues of the potent antibiotic teixobactin could be instrumental in the fight against multi-drug resistant pathogens
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NewsEuropean ‘One Health’ plan aims to curb antimicrobial resistance
Action plan treats human and animal health as interconnected
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ResearchModified antibiotic beats superbug resistance
Adding functional groups to vancomycin gives it extra modes of attack against resistant bacteria
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BusinessPollution from Indian drugmakers drives drug resistance
Areas around manufacturing sites still heavily contaminated with antimicrobials and breeding multidrug-resistant pathogens
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ResearchHow total synthesis is creating antibiotics
Macrolide synthesis could reinvigorate the antibiotic pipeline
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ResearchMaple syrup enhances antibiotics
A phenol-rich mixture extracted from maple syrup allows much smaller doses of antibacterial drugs to achieve the same results
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ResearchPutting the ‘ant’ in antibiotics
Antibacterial polyketides uncovered in the most unusual of places
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News€1 million prize awarded for quick test to cut antibiotic use
Diagnostic device could help fight antimicrobial resistance by determining whether or not an infection is caused by bacteria
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ResearchMolecular structure is teixobactin’s pièce de résistance
Study builds scientists’ arsenal against drug-resistant superbugs
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NewsPharma giants commit to tackling antimicrobial resistance
Plan to tackle superbugs includes changes to manufacturing and sales incentives
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BusinessPfizer to buy Astrazeneca’s antibiotics
Deal tops up Pfizer’s late-stage development pipeline, but AZ will retain biological programmes
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NewsAntibiotic partnership plans accelerated drug development
Public–private venture will invest $350 million over five years but there are warnings that much more money is still needed
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ResearchNew antibiotic picked from nose bacteria
Discovery suggests human microbiome may be an untapped source of antimicrobial compounds
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OpinionWe need a global plan to beat resistance
We all need to do our bit and act for the common good if we’re going to protect antibiotics
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NewsWorld faces tough challenge turning words into action on antibiotic resistance
Countries are waking up to the challenge of ‘superbugs’ but agreeing a way forward will be tricky
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ResearchChemical synthesis injects new life into old antibiotics
Approach can construct wide range of new antibiotic candidates from simple chemical building blocks
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BusinessFDA moves to withdraw swine drug carbadox
Carcinogenic antibiotic has been banned in EU, Canada and Australia for years
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NewsAntibiotic alternatives need to be recruited in fight against resistance
Vaccines, probiotics and other substitutes could help battle antimicrobial resistance as antibiotic effectiveness fades