Antibiotics – Page 2
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ResearchMapping antibiotic’s binding of its target points to way to give drugs the killer edge
Technique that creates a comprehensive catalogue of mutations in antibiotic’s target reveals how drugs might be improved
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ResearchSynthetic peptide mimics can act as antivirals
Peptoids disrupt enveloped viruses’ lipid membranes as well as targeting fungi and bacteria
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BusinessUK antibiotics supply chain stretched by surge in Strep A infections
Government enacts protocols to enable substitute treatments and recommends preventive prescriptions in severe cases
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ResearchSurprise discovery as clam found to be producing complex antibiotic
Erythromycin was previously believed to be only synthesised by bacteria
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ResearchArtificially evolved enzyme tackles tricky cross coupling
Directed evolution on the metalloenzyme cytochrome P450 creates a catalyst for making macrocyclic antibiotics
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ResearchTeixobactin’s two pronged antibiotic attack mechanism revealed
Understanding of formation of deadly supramolecular structures could help build improved antimicrobials
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ResearchMolecular machine drills holes in antibiotic-resistant bacteria killing them
Bacteria aren’t able to develop resistance against nanomotor’s deadly action
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ResearchBreaking bacteria’s genetic silence to synthesise antibiotics that evade resistance
Prospecting in bacterial genomes offers hope in search for new antimicrobial drugs
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BusinessUK takes subscription approach for new antibiotics
Decoupling payment from prescriptions helps preserve last-line antibiotics and encourage R&D
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ResearchGallium helps sneak antibiotic payload into bacterial cells
Compound is more potent than parent drug ciprofloxacin against Staphylococcus aureus
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ResearchBlocking bacteria’s self-poisoning mechanism weakens their antibiotic resistance
Stopping bacteria from producing hydrogen sulfide in response to drugs could help overcome antimicrobial resistance
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BusinessStriving to bolster the antibiotic pipeline before it becomes the next crisis
It’s been almost 10 years since the world was warned of a post-antibiotic apocalypse. Katrina Megget takes a look at the initiatives trying to support antimicrobial R&D
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ResearchMachine learning tool sets out to find new antimicrobial peptides
IBM researchers say their fully automated AI-driven system could speed up the discovery of molecules for novel antibiotics
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NewsOxford University to open antimicrobial research centre after £100m donation from Ineos
Petrochemical giant highlights dangers of antibiotic resistance
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ReviewBiography of Resistance: The Epic Battle Between People and Pathogens
A book illustrating a global health threat more daunting than Covid-19: growing antibiotic resistance
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PodcastBedaquiline
The first TB drug approved in 40 years gave hope to sufferers of drug resistant tuberculosis and ushered in a new class of antibiotics
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OpinionLooking beyond the next wave
We need to apply lessons from Covid-19 to tackle antimicrobial resistance and climate change
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ResearchCheating bacterium becomes antibiotic-tolerant at expense of other species
Coexistence triggers counterintuitive antibiotics response in bacteria, which could be used to tackle hardy species