Headlines
Arkema settles local claims over US hurricane fire emissions
Peroxides producer will pay $1.1 million and make safety improvements
Nicotine analogues emerging in e-cigarettes to evade regulations
Tests show products contain widely variable amounts of compounds with unknown risks
Latest effort to crack down on combination drugs launched by Indian government
Several pharmaceutical firms have launched a challenge to the ban in the supreme court
Being wrong is almost inevitable
On the tightrope of expressing your opinion, you always risk looking a fool
Highlights
The GLP-1 weight loss revolution
Glucagon-like peptide-1 agonist drugs, such as semaglutide, could save countless lives at risk due to diabetes and obesity. Rachel Brazil looks at the difficulties in making the peptides themselves, and what’s coming next
Seaweed success
Scientists and entrepreneurs are sowing the seeds for a new kind of industry. Hayley Bennett explores the buzz around the marine ‘biorefinery’ business – and what might hold it back
Electrification of process heat stands to slash industry’s emissions
Technologies available now can decarbonise most heat demand, but cost and infrastructure barriers still exist
Explainer: Why drug shortages happen and how can we reduce them?
Record-high numbers of drugs are in short supply, from chemotherapy and antibiotics to hormone replacements
Explainer: How is the US pharmaceutical patent system being misused?
What are ‘evergreening’ and ‘thicketing’ and what is being done to reform the system and aid competition?
Driving innovation in the UK’s emerging biotechnology sector
Biotech startups and spinouts must overcome numerous challenges to get from lab to market. A new UK innovation hub aims to give this emerging sector the space, resources and expertise it needs.
Latest effort to crack down on combination drugs launched by Indian government
Several pharmaceutical firms have launched a challenge to the ban in the supreme court
Being wrong is almost inevitable
On the tightrope of expressing your opinion, you always risk looking a fool
GLP-1 drugs could be more than a win–win for weight loss
Semaglutide and tirzepatide are changing lives, and could change our attitudes
The GLP-1 weight loss revolution
17 dead in solvent explosion at Indian plant
MDMA rejection poses questions for psychedelic drug trials
AI meets chemistry: Standigm’s breakthrough with Synthia Retrosynthesis Software
Medicinal chemistry’s biological blind spots
Explainer: Why drug shortages happen and how can we reduce them?
Arkema settles local claims over US hurricane fire emissions
Peroxides producer will pay $1.1 million and make safety improvements
Nicotine analogues emerging in e-cigarettes to evade regulations
Tests show products contain widely variable amounts of compounds with unknown risks
MDMA rejection poses questions for psychedelic drug trials
Decision prompts reflection over how psychotherapy is involved, regulating combination treatments and safeguarding patients
China cracks down on fentanyl precursor chemicals
Three fentanyl chemical ingredients will be subject to new restrictions from September
Explainer: Why drug shortages happen and how can we reduce them?
Record-high numbers of drugs are in short supply, from chemotherapy and antibiotics to hormone replacements
Explainer: How is the US pharmaceutical patent system being misused?
What are ‘evergreening’ and ‘thicketing’ and what is being done to reform the system and aid competition?
Therapeutic proteins can hitch a ride on parasite to bypass blood-brain barrier
Toxoplasma could be delivery agent for protein drugs – provided parasite can be made safe
Drugs and vaccines could be freed from cold chains by hydrogel
Stiff gel prevents proteins from aggregating, preserving their therapeutic power
Companion compound for naloxone could boost opioid reversal effects, save lives
Discovery could help in fight against super-strength opioids such as fentanyl
Recycled construction waste could cut cement and steel’s carbon footprint
Cement can be regenerated during steel recycling in an electric arc furnace
Conjugate vaccine curbs xylazine effects in mice
Proof-of-concept for therapy that harnesses immune system to fight fentanyl adulterant
Simplified hydroformylation replaces rhodium with base metal
Bench-friendly asymmetric hydroformylation swaps toxic gas and expensive catalyst for cheap reagents and mild conditions
‘Late-stage saturation’ could improve drugs' effectiveness
Approach turns flat aromatic structures into three-dimensional saturated molecules with improved medicinal properties
How HIV drugs have changed over the decades
From one big pill that only prolonged lives a few months, through the 20 pills a day years to modern combination therapies, treating HIV is a science success story
Seaweed success
Scientists and entrepreneurs are sowing the seeds for a new kind of industry. Hayley Bennett explores the buzz around the marine ‘biorefinery’ business – and what might hold it back
How DDT went from triumph to tragedy
Few compounds have a story as controversial as this insecticide. Mike Sutton traces the tale from its beginning 150 years ago
Beating the heat problem
Electrifying process heat is a cost problem, not a technical one
Electrification of process heat stands to slash industry’s emissions
Technologies available now can decarbonise most heat demand, but cost and infrastructure barriers still exist
Arkema settles local claims over US hurricane fire emissions
Peroxides producer will pay $1.1 million and make safety improvements
17 dead in solvent explosion at Indian plant
Dozens more injured at pharmaceutical ingredients manufacturer in Andhra Pradesh
Beating the heat problem
Electrifying process heat is a cost problem, not a technical one
Seaweed success
Scientists and entrepreneurs are sowing the seeds for a new kind of industry. Hayley Bennett explores the buzz around the marine ‘biorefinery’ business – and what might hold it back
Electrification of process heat stands to slash industry’s emissions
Technologies available now can decarbonise most heat demand, but cost and infrastructure barriers still exist
Red Sea attacks are reshaping chemical supply chains
High demand and reduced capacity have kept freight prices high
Weight-loss drugmakers bet billions on boosting supplies
Eli Lilly and Novo Nordisk invest to expand in-house manufacturing of GLP-1 drugs
Job cuts sweeping across pharmaceuticals
Several big firms cutting deep to reduce costs
Pan-cancer approval shows huge potential for antibody–drug conjugates
Enhertu gains approval based on gene expression rather than tumour location
Optimising synthesis: SYNTHIA & green chemistry
Reduce step counts, improve yields and atom economy while reducing environmental impact, all with a little computational help
From R&D to QC, making NMR accessible for everyone
Putting NMR spectroscopy at the heart of the analytical chemistry lab
Accelerating scientific discovery with cutting-edge computing
Learn how to accelerate discovery in chemistry and materials science by integrating the latest breakthroughs in High-performance computing, AI and quantum computing
