Headlines

BioLab fire

Fire at US pool chemical plant releases huge chlorine plume

Thousands of residents evacuated and kept indoors as as smoke and gas cloud persists for days

Cobenfy

US approves schizophrenia drug with new mode of action

Cobenfy promises to better address negative symptoms than existing antipsychotics

Morning glory and poppy

A chemist in the flower garden

The beautifully complex molecules plants produce are as inspiring as the blooms themselves

Single use plastic

California sues ExxonMobil over misleading plastic recycling claims

Suit claims firm used false claims to justify producing vast amounts of single-use plastics

Highlights

A semaglutide injecting 'pen' wrapped in a napkin with a knife and fork, on a red gingham tablecloth, next to a white plate

The GLP-1 weight loss revolution

Glucagon-like peptide-1 agonist drugs, such as semaglutide, could save countless lives at risk due to diabetes and obesity. Rachel Brazil looks at the difficulties in making the peptides themselves, and what’s coming next

Sugar kelp

Seaweed success

Scientists and entrepreneurs are sowing the seeds for a new kind of industry. Hayley Bennett explores the buzz around the marine ‘biorefinery’ business – and what might hold it back

A thermogram showing hot industrial smoke stacks

Electrification of process heat stands to slash industry’s emissions

Technologies available now can decarbonise most heat demand, but cost and infrastructure barriers still exist

Medicine bottles on a pharmacy shelf marked as empty

Explainer: Why drug shortages happen and how can we reduce them?

Record-high numbers of drugs are in short supply, from chemotherapy and antibiotics to hormone replacements

NovoRapid and NovoLog

Explainer: How is the US pharmaceutical patent system being misused?

What are ‘evergreening’ and ‘thicketing’ and what is being done to reform the system and aid competition?

Cobenfy

US approves schizophrenia drug with new mode of action

Cobenfy promises to better address negative symptoms than existing antipsychotics

Looking down on a number of neatly arranged vials containing blood on a pink desk

The science and promise of liquid biopsies

Join us on 4 December to learn more about the science of liquid biopsies from leaders in the field

Morning glory and poppy

A chemist in the flower garden

The beautifully complex molecules plants produce are as inspiring as the blooms themselves

3D visualisation of nicotinic acid model on periodic table background.

Copper-catalysed carbon-heteroatom bond-forming processes

Sponsored by

Join us 15 October to explore cutting edge copper-catalysed carbon-heteroatom bond formations used in industrial applications

BioLab fire

Fire at US pool chemical plant releases huge chlorine plume

Thousands of residents evacuated and kept indoors as as smoke and gas cloud persists for days

California sues ExxonMobil over misleading plastic recycling claims

Suit claims firm used false claims to justify producing vast amounts of single-use plastics

Three indicted in US for smuggling pool chemicals from China

Defendants face fines and jail for illegally importing and distributing trichloroisocyanuric acid

Tea tree oil faces ban in UK and EU over reprotoxicity

Defenders question relevance of animal safety data that triggered decision

US industry braced for change as election looms

Regulation, trade tariffs and innovation support top lists of concerns

Dacthal herbicide withdrawn in US over risks to foetal development

Sole supplier American Vanguard has cancelled US and international registrations

Toxoplasma

Therapeutic proteins can hitch a ride on parasite to bypass blood-brain barrier

Toxoplasma could be delivery agent for protein drugs – provided parasite can be made safe

Medications stored in a fridge

Drugs and vaccines could be freed from cold chains by hydrogel

Stiff gel prevents proteins from aggregating, preserving their therapeutic power

An emergency overdose kit on a street providing Naloxone

Companion compound for naloxone could boost opioid reversal effects, save lives

Discovery could help in fight against super-strength opioids such as fentanyl

Recycled construction waste could cut cement and steel’s carbon footprint

Cement can be regenerated during steel recycling in an electric arc furnace

Conjugate vaccine curbs xylazine effects in mice

Proof-of-concept for therapy that harnesses immune system to fight fentanyl adulterant

Simplified hydroformylation replaces rhodium with base metal

Bench-friendly asymmetric hydroformylation swaps toxic gas and expensive catalyst for cheap reagents and mild conditions

‘Late-stage saturation’ could improve drugs' effectiveness

Approach turns flat aromatic structures into three-dimensional saturated molecules with improved medicinal properties

How HIV drugs have changed over the decades

From one big pill that only prolonged lives a few months, through the 20 pills a day years to modern combination therapies, treating HIV is a science success story

BioLab fire

Fire at US pool chemical plant releases huge chlorine plume

Thousands of residents evacuated and kept indoors as as smoke and gas cloud persists for days

Three indicted in US for smuggling pool chemicals from China

Defendants face fines and jail for illegally importing and distributing trichloroisocyanuric acid

Tea tree oil faces ban in UK and EU over reprotoxicity

Defenders question relevance of animal safety data that triggered decision

Arkema settles local claims over US hurricane fire emissions

Peroxides producer will pay $1.1 million and make safety improvements

17 dead in solvent explosion at Indian plant

Dozens more injured at pharmaceutical ingredients manufacturer in Andhra Pradesh

Beating the heat problem

Electrifying process heat is a cost problem, not a technical one

Illustration of an electrosynthesis setup in a lab, showing electricity, chemical reactions, and lab equipment like flasks

Electrochemistry: a powerful addition to the synthetic chemistry toolbox

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In this free download, discover how advancements in electrochemical techniques can broaden the scope and impact of chemical synthesis

Index image

Optimising synthesis: SYNTHIA & green chemistry

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Reduce step counts, improve yields and atom economy while reducing environmental impact, all with a little computational help

Index

From R&D to QC, making NMR accessible for everyone

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Putting NMR spectroscopy at the heart of the analytical chemistry lab