All natural products articles
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Opinion(−)-Novofumigatonin
Oxidations abound in this satisfying synthesis, with a delicate nitrile hydrolysis to finish
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OpinionA chemist in the flower garden
The beautifully complex molecules plants produce are as inspiring as the blooms themselves
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OpinionEnormous enzymes expand the limits of molecular biology
Identifying the PKZILLAs, used by algae to make toxins, stretched the capabilities of current analytical methods – and the limits of our preconceptions
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ResearchUnderwater device reveals marine chemical diversity
I-Smel device probes metabolites produced by Mediterranean sponges
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ResearchAncient microbial natural products reconstructed from Neanderthal dental plaques
Palaeogenomic approach allows natural product researchers to ‘go back in time’
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BusinessNature-inspired crop protection
Plant extracts, proteins and pheromones aiming to replace conventional chemical pesticides
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ResearchCo-crystals fish out cannabinoid from plant extract
Purifying cannabidiol from natural cannabis extract made cheap and easy thanks to amino acid partner
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WebinarMobile mass spectrometry – taking the laboratory to the field
Learn how compact mobile mass spectrometry enables researchers to sample on-the-spot in a field environment, for instant mass analysis and real-time decision making within seconds
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ResearchGenentech antibiotic quells resistance
Modified arylomycin combines high potency with new mechanism of action
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ResearchFour step route to carbotricycles
Elegant strategy that directly assembles 5–8–5 scaffolds from simple precursors paves way to a new library of bioactive compounds
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ResearchWhat’s left isn’t always right in total synthesis
Scientists turn detective to solve a decade-old stereochemical enigma
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ResearchSuper-electrophilic ions enable selective modification of bioactive molecules
New technique will help medicinal chemists explore chemical space
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OpinionThat’s stereochemistry
Recognising the tetrahedral nature of carbon changed science as well as explaining it
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ResearchPutting the ‘ant’ in antibiotics
Antibacterial polyketides uncovered in the most unusual of places
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ResearchDibrominated tag helps identify new natural products
New substance allows researchers to find new aldehyde- and ketone-containing natural products
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NewsAkzoNobel sponsors colour garden at Chelsea Flower Show
Display celebrates plants that have been used historically to make dyes, and highlights a new project to capture nature’s structural colours in paint
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ResearchNew antibiotic could treat infection while dodging resistance problems
Technique to tap huge unexplored reservoir of natural products in soil microorganisms finds promising compound