All Reactions and synthesis articles – Page 23
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ResearchProgram finds 5 million synthetic routes to complex chemicals
Only around five hundred ‘tactical combinations’ for advanced organic synthesis existed – until Chematica was let loose on the problem
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ResearchCompact pharmaceutical factory manufactures drugs on demand
Plant with modular design would occupy about half the area of a squash court
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ResearchGrinding out single-atom catalysts made simple by ball mill
No compromise on quality of heterogeneous catalysts made on kilogram scale
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ResearchTotal synthesis of H. pylori antigen creates starting point for gastric cancer vaccine
Remote participation strategy helps chemists make sterically-congested repeating fragment
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ResearchCatalyst breaks sulfur–sulfur bonds to give new life to tired tyres
Process recovers organic components that can become new elastomers
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ResearchIntense sound fields make mercury react with water
After nearly a century, scientists can explain why a grey cloud forms when mercury and water are sonicated
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ResearchSimple way to construct molecules with perfluoroalkyl bridges
Troublesome side reaction becomes useful synthetic tool
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NewsOpen access Atlas maps out microbial natural products
Project aims to accelerate research on microbial metabolites
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Research‘Ideal’ water splitting catalysts actually exist, simulations find
New computational model could accelerate the discovery of cheaper and more efficient catalysts
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OpinionCleaning up chemical kitchens
In a busy plant, ensuring small changes don’t produce unforeseen toxic impurities is key
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ResearchFlow synthesis produces chiral intermediate for antidepressant drug
The first solvent-free organocatalytic flow process yields the key chiral intermediate for paroxetine on a multigram-scale
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ResearchTotal synthesis of unnatural enantiomer renews interest in quinine
Scientists hope their strategy will invigorate cinchona alkaloid-mimic catalysis
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ResearchChemists taken aback as dinitrogen found to speed up some reactions
Warnings that nitrogen should no longer be considered just an inert carrier gas
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ResearchBiomimetic synthesis cultivates yellow poppy pigment
Cascade process that fuses indole with orientalin verifies biosynthesis of nudicaulins
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ResearchSteric shield leads boron to aromatic rings’ most remote region
Bulky blocking counterion makes quick work of borylating arenes’ inaccessible para position
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Opinion(±)-Rhabdastrellic acid A
A triterpene that looks innocuous until it reveals the highly strained conformation of its rings
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ResearchLight intensity changes can switch photocatalyst between one- and two-photon mechanisms
Simple optical lens behind strategy for manipulating photochemical reactivity