All Totally synthetic articles

  • Ciguatoxin CTX1B
    Opinion

    Gone to completion

    2013-11-26T00:00:00Z

    After a 66-step journey, Paul Docherty ponders the future of total synthesis in his final column

  • Marcfortines B (left) and C (right)
    Opinion

    Marcfortines B & C

    2013-11-05T00:00:00Z

    Paul Docherty ponders a tasty cheeseboard as a source of synthetic inspiration

  • 1013CW-TOT-SYN-Main_300
    Opinion

    Scholarisine A

    2013-09-26T00:00:00Z

    Paul Docherty marvels at a parade of intricate radical reactions

  • Steviol
    Opinion

    Steviol

    2013-09-02T00:00:00Z

    Sculpting a molecule from a larger whole is an unusual but effective strategy, says Paul Docherty

  • Opinion

    Melotenine A

    2013-07-30T00:00:00Z

    Paul Docherty extols the virtues of chiral heteroatoms

  • Opinion

    Bolivianine

    2013-06-27T00:00:00Z

    A complex terpene gives Paul Docherty a headache

  • Opinion

    Pactamycin

    2013-05-29T00:00:00Z

    Labelling a molecule 'inaccessible to synthesis' is a red rag to a bull, says Paul Docherty

  • Opinion

    Kingianin A

    2013-05-01T00:00:00Z

    Paul Docherty faces his fears of frontier molecular orbital theory

  • Opinion

    Acutumine

    2013-03-22T00:00:00Z

    Polycyclic acutumine ties Paul Docherty up in knots

  • Opinion

    Lyconadin A again

    2013-02-28T00:00:00Z

    Paul Docherty tackles a serious repeat offender

  • Opinion

    Hyperforin

    2013-01-24T00:00:00Z

    A flexible natural product synthesis is the key to later drug development

  • Opinion

    Flueggine A

    2013-01-02T00:00:00Z

    Some exotic heterocyclic chemistry catches Paul Docherty's eye

  • Opinion

    Pentalenolactone A methyl ester

    2012-11-27T00:00:00Z

    Paul Docherty revises a reaction he never could quite remember

  • Opinion

    Epicoccin G

    2012-10-31T00:00:00Z

    Paul Docherty gets to grips with some thiodiketopiperazines

  • Opinion

    Prostaglandin F2α

    2012-10-01T00:00:00Z

    Paul Docherty comes face to face with an old adversary

  • Opinion

    Amphidinolide F

    2012-08-29T00:00:00Z

    Symmetry in natural products isn’t always so apparent

  • Opinion

    Marinomycin A

    2012-07-27T00:00:00Z

    Faced with the term ‘polymer’, most people would consider man-made materials

  • Opinion

    Vincorine

    2012-07-01T00:00:00Z

    Cage-structured natural products are some of the most appealing targets for organic chemists

  • Opinion

    atrop-Abyssomicin C

    2012-05-31T00:00:00Z

    Natural products frequently have hard to pronounce and even harder to spell names, often of little meaning.

  • Opinion

    Hopeahainol A and hopeanol

    2012-04-30T00:00:00Z

    This month's synthesis looks somewhat familiar