Biology – Page 33
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WebinarMiniaturise the haystack: DNA-Encoded Libraries for drug discovery
A DNA-Encoded Library (DEL) case study and fragment-based DEL discovery insight from DyNAbind
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ResearchImpact of extra-terrestrial glycine delivery could have created nucleobase precursors
Quantum simulations show that comets and other celestial bodies may have not only delivered building blocks for life to Earth, but also synthesised them on impact
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ResearchChinese gene-edited babies at higher risk of premature death
Loss of gene knocked-out by rogue geneticists found to be linked with higher mortality in human genome database
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BusinessUS finalises guidance on biosimilars
Regulator clarifies requirements for allowing substitution between products
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NewsIllegally grown GM aubergines highlight India’s continuing ambivalence to transgenic crops
Discovery has revived protests against the technology
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NewsInternational commission launched to tackle tough questions around gene-editing
US and UK scientific academies have convened a new body charged with developing a global framework for heritable human genome editing
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OpinionThe crowdsourced analysis hoping to go viral
Crowdsourcing image analysis to better understand how viruses multiply inside cells
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FeatureChanging the locks
Designer receptors help understand cellular signals and could treat epilepsy and Parkinson’s disease, but need new tools, finds Andy Extance
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NewsDarpa wants to genetically engineer soldiers’ skin bacteria to protect them from mosquitoes
Pentagon programme aims to change chemical cues released by human skin microbes to provide a long-term defence from mosquito-borne diseases
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ReviewChasing the Sun: The New Science of Sunlight and How it Shapes Our Bodies and Minds
Jonelle Harvey takes us through Linda Geddes’ new book
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ResearchEnzyme evolved to selectively functionalise carbon–hydrogen bonds
Lactam libraries created by engineered bacterial enzyme offer new way to fight antibiotic resistance
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ResearchFirst bacterium with a totally redesigned genome created
Designer E. coli uses a simplified genetic code to make proteins
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PodcastMethylphenidate (Ritalin)
Jamie Durrani diverts his attention to the rise of Ritalin, a drug first identified as a way of improving tennis performance
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PodcastClearing the air by Tim Smedley – Book club
Tim Smedley travels the world to work out why air pollution occurs, and what we can do to solve the problem
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ResearchCrispr gene-editor helps find new treatments for box jellyfish venom
Cyclodextrins show promise treating stings
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ResearchNeural network folds proteins a million times faster than its competitors
Machine learning algorithm that predicts protein structures in milliseconds could top next protein folding contest
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ResearchFood colouring paves the way for 3D-printed organs
Tatrazine could overcome biocompatibility problems of printed tissues
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ResearchSwitching to sulfur stops deadly bacteria growth
Modified sugar prevents growth of Clostridium difficile while retaining useful properties
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PodcastLimulus Amebocyte Lysate
Frances Addison takes a look at the discovery that brought horseshoe crabs to the heart of the pharmaceutical industry
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ResearchEnzyme redesign magnifies rare sugar synthesis
Tweaks could allow scientists to explore the commercial potential of an unusual disaccharide found in Japanese sake