Drug discovery and development – Page 17
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BusinessThis little Crispr went to market
Gene editing technology heading towards commercial reality in pharmaceuticals, food and organ transplant
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OpinionAlice Ball’s treatment for leprosy
Nina Notman tells the overlooked story of historic African-American chemist Alice Ball who developed the first partially-effective treatment for leprosy
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OpinionHopes and fears for remdesivir
Available resources for testing coronavirus treatments need to be used wisely
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OpinionDoes the drug work, or not?
Coronavirus trials reveal the murky reality of disentangling compounds’ effects on human biology
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PodcastInterferon beta
An immune-modulating compound used to reduce the symptoms of multiple sclerosis and now showing potential against coronaviruses
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ResearchIntroducing chirality to give organic electronics a twist
Medicinal molecules and electronic materials aren’t often found in the same research group. Meet Matthew Fuchter, who’s excelling at both
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BusinessPostEra points its synthesis algorithm at coronavirus
Mapping out drug discovery routes with artificial intelligence
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NewsScience steps up a gear as struggle to both understand and fight coronavirus intensifies
Research that might have taken years is being turned around in months as journals fast-track Covid-19 manuscripts
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NewsOpen source antiviral dataset released to aid fight against Covid-19
CAS collection hosts 50,000 compounds with potential to treat coronavirus infections
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NewsPublisher expresses reservations about hydroxychloroquine study it printed
Study claimed malaria drug could treat Covid-19
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PodcastRemdesivir
Will new clinical trials for Covid-19 give remdesivir a second chance? Ben Valsler introduces the broad-spectrum antiviral that didn’t quite make it as the Ebola drug it was originally planned to be
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ResearchStructural studies offer glimpse of how coronavirus initiates human cell invasion
Researchers studying virus receptor-binding domains suggest virus could have passed directly from bats to humans
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OpinionVaccine development against the clock
How long will it take to develop a coronavirus vaccine and why is it so hard?
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BusinessCan existing drugs slow Covid-19?
The fastest route to treatments may be to repurpose existing drugs – if they work
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PodcastChloroquine and hydroxychloroquine
The Covid-19 pandemic – and some very high profile backing – has led to malaria drugs chloroquine and hydroxychloroquine hitting the headlines worldwide.
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ResearchPotent coronavirus drug candidate designed using 3D structure of key viral enzyme
Inhibitor of Sars-CoV-2 protease shows promise in early animal tests