Drug discovery and development – Page 20
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ArticleArtificial intelligence: on the cusp of a digital revolution
AI is transforming the pharma industry and its drug discovery pipeline
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FeatureSeparating turmeric fact from fiction
Thousands of papers have been published on curcumin’s healing potential, but its usefulness is not yet proven, finds Andy Extance
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OpinionWill computers ever discover drugs from scratch?
With enough understanding and computing power, it should be possible, but will it happen?
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WebinarAdvantages of characterising pharmaceuticals using DSC and TGA
Learn how APIs, excipients and formulations can be investigated by differential scanning calorimetry and thermogravimetric analysis
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WebinarAI and deep learning for chemistry with Pipeline Pilot
Learn how teams can effectively collaborate, manage and implement machine learning using Pipeline Pilot from Dassault Systèmes
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BusinessThe rise of venture philanthropy
More and more charities are investing in companies, and looking for returns on that investment, as an alternative to traditional grants
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ResearchAlzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
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ResearchMetallohelices emulate antimicrobial peptides
Scientists move away from traditional drug candidates to evade resistance
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BusinessSixth in a line of Alzheimer’s drugs fails in trials
Treatments designed to stop amyloid peptide formation all seem to cause cognitive impairment rather than prevent it
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ArticleThe importance of solid form science in modern drug development
A recent study suggests that around 40% of drugs with market approval exhibit poor water solubility and although this is not a new problem, solutions like those offered by Johnson Matthey are still relevant to today’s pharma market
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ResearchElusive protein and key to many tropical diseases found after decades of searching
Discovery offers powerful new target to treat trypanosome parasite illnesses that affect millions
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OpinionEmbracing structural disorder
Medicinal chemists need to overcome their fear of fuzzy proteins
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ResearchRetrosynthetic algorithm broadened to design similar, but different, molecules
Chematica can now design efficient syntheses for large compound libraries
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ArticleAccurate temperature control achieving big results, on a small scale
Radleys’ compact reaction station brings accurate temperature control to chemical scientists managing small-scale experiments
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OpinionAre new drugs better than existing ones?
Should companies be made to change the way they run clinical trials?
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ResearchModified metallohelices show medical potential
Post-assembly click reactions on helical metal complexes produces biological activity akin to that of the arrow poison ouabain
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