Drug discovery and development – Page 18
-
BusinessCan existing drugs slow Covid-19?
The fastest route to treatments may be to repurpose existing drugs – if they work
-
PodcastChloroquine and hydroxychloroquine
The Covid-19 pandemic – and some very high profile backing – has led to malaria drugs chloroquine and hydroxychloroquine hitting the headlines worldwide.
-
ResearchPotent coronavirus drug candidate designed using 3D structure of key viral enzyme
Inhibitor of Sars-CoV-2 protease shows promise in early animal tests
-
NewsUK researchers receive £20m to start coronavirus treatment research
Two vaccine trials among six projects that win funding
-
ArticleMetathesis enables everyday innovation
For process chemists, simple solutions to complex problems are crucial. Metathesis is a cost-effective, reliable and scalable tool that enables innovation
-
ArticleMarrying personalised medicine with the mainstream
By eliminating waste and confronting supply chain issues, the Medicines Manufacturing Innovation Centre is bringing personalised medicine to healthcare
-
-
ResearchTargeted nanoparticles swell-up to kill cancer cells
Nanoparticles covered with charged ligands can kill errant cancer cells but leave normal cells unharmed
-
PodcastMinoxidil and Finasteride
Catherine Hodges explores the chemical solutions to thinning hair and patchy beards, examining the popularity of minoxidil and the cautionary tale of finasteride
-
BusinessRNA vaccines are coronavirus frontrunners
Several groups have potential Sars-CoV-2 vaccines ready or close to testing, thanks to rapid development pathways
-
ResearchCheating bacterium becomes antibiotic-tolerant at expense of other species
Coexistence triggers counterintuitive antibiotics response in bacteria, which could be used to tackle hardy species
-
ResearchMetal complexes outperform organics in antimicrobial analysis on crowdsourced compounds
Could this study prompt drug developers to rethink their reluctance to making metal-based pharmaceuticals?
-
ResearchAI tool screens 107 million molecules, discovers potent new antibiotics
Deep learning approach could help in fight against drug-resistant bacteria
-
ResearchDetailed 3D coronavirus spike map offers hope for vaccine development
Structure determined at ‘remarkable’ speed in little over a month
-
OpinionTwo heads are better than one
Bifunctionals show that sometimes simply tethering two useful molecules together unlocks some useful activity
-
FeatureAdjuvants: vaccines’ hidden helpers
Anthony King examines a crucial part of vaccines that can significantly boost their performance, but which often go unrecognised
-
BusinessThe race to fight coronavirus
While genome sequences enable testing and vaccine efforts, companies are donating existing antiviral drugs to explore repurposing
-
ArticleTransforming innovation for startups
Green polymer specialists Novomer and biotech startup SynbiCite optimised industrial and biotech processes using design of experiment software from JMP
-
FeatureThe search for cancer vaccines
Claire Jarvis looks at ongoing work to prevent the disease – and convince a sceptical community of their seriousness
-
BusinessCancer and rare diseases dominated 2019 drug approvals
More streamlined review processes and changing R&D priorities have contributed to sustained increase in new medicines