Drug discovery and development – Page 21
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ArticleThrough the looking glass: a digital future for healthcare
As the digital revolution continues to disrupt even the world’s most established business sectors, the pharmaceutical industry will need to shift and adapt if it is to realise its vision for the future of healthcare
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ArticleMultidisciplinary science kick starts innovation
Nanoform scientists discuss how their diverse personalities and scientific backgrounds foster innovation, helping them tackle problems from different angles, and design better processes
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OpinionThe silent rise of the robots
Mechanical helpers have been creeping into our labs for decades
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PodcastCyclopropane
Chemistry’s tastiest bonds for an explosive anaesthetic that was as useful as it was dangerous
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Podcast2C psychedelics
A class of hallucinogenic phenethylamines, explored by the 'godfather of psychedelics' Alexander Shulgin and sadly implicated in a tragedy at a 2017 music festival
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ResearchColourful antibiotics isolated from scorpion venom
Isolated benzoquinone has excellent activity against TB along with low toxicity in mice
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PodcastAzidothymidine
The first drug approved in the US to treat Aids required a completely new approach to clinical trials – Frances Addison explores the history of azidothymidine
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OpinionIs this a golden age of new drug classes?
A host of new treatment modes are hitting the clinic and the market
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ResearchSpore shell acts as sunscreen for light-sensitive antibiotics
Polymer capsule that protects and preserves antimicrobial compound could aid fight against multi-drug resistant pathogens
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PodcastAmantadine
Katrina Krämer investigates how one of the smallest small molecule drugs around saved Jeanna Giese's life
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WebinarMiniaturise the haystack: DNA-Encoded Libraries for drug discovery
A DNA-Encoded Library (DEL) case study and fragment-based DEL discovery insight from DyNAbind
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BusinessUS finalises guidance on biosimilars
Regulator clarifies requirements for allowing substitution between products
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ResearchTrefoil knots steer cancer drug leads in fresh direction
Chemists look to links and knots in the search for new cancer therapies
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FeatureChanging the locks
Designer receptors help understand cellular signals and could treat epilepsy and Parkinson’s disease, but need new tools, finds Andy Extance
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PodcastMethylphenidate (Ritalin)
Jamie Durrani diverts his attention to the rise of Ritalin, a drug first identified as a way of improving tennis performance
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FeatureMalaria no more?
Efforts to cure malaria have been going on for hundreds of years. Clare Sansom looks at some of the latest – and most innovative
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NewsPilot malaria vaccination programme begins in Malawi
Mosquirix vaccine will be rolled out in Ghana and Kenya next week
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ResearchSynthetic enzyme wipes out tough bacterial biofilms
After success in mice strategy could be an alternative to antibiotics to treat wounds