Medicinal chemistry – Page 18
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NewsRussian opposition leader was poisoned with Novichok agent
German chancellor Angela Merkel says Russia has ‘serious questions’ to answer after tests confirm presence of nerve agent in Alexei Navalny’s bloodstream
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OpinionFacing the challenge of vaccine trials
Russia’s Covid-19 gamble is a stark contrast to even accelerated clinical programmes
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BusinessRussian vaccine launch shocks scientists
Sputnik V to be approved without large human trial data
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ResearchMass spectrometry and augmented reality guide tumour removal in real time
Colour pixels help surgeons differentiate between cancerous and healthy tissue
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BusinessEncouraging signs from initial Covid-19 vaccine trials
Human trials deliver positive immune responses, while primate challenge studies suggest protection is possible
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FeatureWhy is cystic fibrosis so hard to treat?
Claire Jarvis talks to the scientists trying to find new drugs to treat the inherited lung condition
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ResearchTranslating snail venom research from beach to bench and beyond
Meet Mandë Holford, an interdisciplinary scientist following tangents that arise when exploring the molecular-level workings of venom peptides
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PodcastFavipiravir
Originally developed to treat flu and marketed in Japan as Avigan, promising Covid-19 trial results have seen countries stockpiling this medication by the millions
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OpinionQuestioning European policy on alkyl mesylate impurities
Policies based on false hypotheses can persist in spite of overwhelming contradictory data
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WebinarIlluminating research with the LightOx PhotoReact 365 benchtop photoreactor
Learn about the LightOx PhotoReact – a benchtop photoreactor enabling reproducible irradiation for photochemical and photobiological applications
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PodcastTannic acid
Tannic acid in green acorns can kill wild animals and livestock, but you can prevent poisoning with pannage pigs
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BusinessAppeals court cuts damages further in glyphosate cancer case
Judgment retains verdict that Bayer-Monsanto’s herbicide caused US man’s cancer
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ResearchCommon inactive drug ingredients not as inert as thought
38 out of 639 excipients tested interact with toxicity-related proteins, some reaching levels that might produce unwanted effects
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OpinionLooking beyond the next wave
We need to apply lessons from Covid-19 to tackle antimicrobial resistance and climate change
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NewsHand-powered centrifuge setup can diagnose Covid-19 for just a dollar a test
$5 centrifuge based on children’s toy part of raft of cheap technologies that can detect the virus in saliva in remote locations
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ResearchAlgorithm predicts mortality of Covid-19 patients from blood biomarkers
Artificial intelligence tool to help doctors prioritise treatment
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NewsDoes hydroxychloroquine still have a role to play in this pandemic?
Touted as a wonder drug by some its star now appears to be on the wane
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BusinessWhat are the risks of fast-tracking a Covid-19 vaccine?
Condensing timelines from years to months inevitably involves compromises
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OpinionGhanaian biochemistry TV star Marian Addy
Marian Addy was the first female science professor in Ghana, who studied herbal medicine – and was a TV star