Medicinal chemistry – Page 17
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WebinarSpeed up process development by making more from your offline and online data
Learn how the biotechnology R&D team at Clariant uses statistical modelling techniques to speed up the process development of their bio-ethanol product
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ResearchPepto-Bismol compound’s structure unveiled after 120 years
Electron microscopy triumphed over x-ray crystallography as century-old structural puzzle around bismuth subsalicylate is finally solved
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BusinessUK takes subscription approach for new antibiotics
Decoupling payment from prescriptions helps preserve last-line antibiotics and encourage R&D
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NewsUK’s non-profit vaccine manufacturing centre sold off before opening
Pharmaceutical firm Catalent buys government-backed facility near Oxford
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FeatureA decade of CAR-T cell therapy
Nina Notman looks at the revolutionary treatment already taking on cancer, now aiming for wider use
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ArticleNanotechnology for a healthier, cleaner world for all
Using novel polymer fluorophores to study, detect and treat life-threatening diseases
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NewsDrug discovery AI that developed new nerve agents raises difficult questions
Researchers shocked by how easily algorithm discovered novel poisons even deadlier than VX
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OpinionA spanner in the works
Most drugs work by breaking or stopping something, rather than by making something faster or better
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BusinessModerna sued over Covid-19 vaccine-related patents
Arbutus and Genevant say lipid nanoparticles that protect mRNA infringe six key patents
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FeatureSequencing one cell at a time
New advances that allow scientists to uncover the molecular differences between individual cells could revolutionise medicine, Ian le Guillou finds
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![Terphen[3]arene](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/100x67/7/3/6/518736_d2cc00040gf1_733670.jpg)
ResearchSulfonated macrocycle helps the medicine go down
A supramolecular approach makes alkaloid drugs taste less bitter
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ResearchArray of compounds found in plastics promote fat cell formation in vitro
A third of thousands of chemicals that leach from consumer polymers linked to the development of fat cells
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BusinessTrials start of mRNA vaccine for HIV
First steps towards protection from the many and variable viral strains
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ResearchLeft-handed nanoparticles are far better vaccine adjuvants than their mirror images
Chiral gold nanoparticles shown for the first time to elicit differing immune responses in cells and live mice
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NewsExplainer: How do the Covid vaccines measure up against each other and omicron?
Looking at how the evidence stacks up for vaccines against variants and how their performance holds up over time
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OpinionLetters: February 2022
Readers investigate June Lindsey’s legacy, question policy and celebrate vaccination
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OpinionThe shadow of drug resistance
Why do some medicines stop working, and can we avoid it for Covid-19 antivirals?
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BusinessMartin Shkreli fined and banned from pharma for life
‘Pharma Bro’ must pay back $65m in profits for anticompetitive behaviour while leading Turing Pharmaceuticals
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OpinionThe law of conservation of data
AI and machine learning are useful and powerful, but they need high quality data inputs that aren’t available yet for drug discovery
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ResearchGreen credentials of crystallisation process turned around by rotary cone dryer tweak
Mechanochemistry helps transformations and cocrystallisations cut solvent use on an industrial scale