Medicinal chemistry – Page 20
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BusinessStriving to bolster the antibiotic pipeline before it becomes the next crisis
It’s been almost 10 years since the world was warned of a post-antibiotic apocalypse. Katrina Megget takes a look at the initiatives trying to support antimicrobial R&D
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ResearchPollen-mimicking antidote saves bees after pesticide exposure
Calcium carbonate microparticles deliver detoxifying enzyme to bees’ guts
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NewsPromotion of Covid-19 pseudoscience by Indian government criticised as pandemic rages
Questionable therapies under study or promoted include prayer, breathing exercises and herbal medicines
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OpinionThe side effects of being unique
Even the largest clinical trials won’t capture all possible bad reactions to a drug – we need pharmacovigilance
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ResearchClick chemistry uses endogenous acrolein to activate cancer prodrug
Strategy could reduce chemotherapy side effects by selecting for cancerous cells
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NewsUS onboard with effort to waive global Covid-19 vaccine patents
Biden administration says pandemic calls for ‘extraordinary measures’ to relinquish IP protections, but pharma and biotech sectors push back
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OpinionEmbracing the exposome
Analytical research strategies are evolving to keep up with the chemical complexities of our world
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OpinionLetters: May 2021
Readers ponder hydrogel vaccine distribution and life with hearing difficulties
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ResearchTri-agonist molecule designed to stimulate immune system crosstalk
Conjugation chemistry connects three different agonists around a triazine core
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NewsUS urged to waive Covid-19 vaccine patents
175 former world leaders and Nobel laureates call on Joe Biden to suspend intellectual property rules
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WebinarMolecular modeling for the medicinal chemistry toolkit
Join us to discover how to streamline your workflows using integrated software solutions for docking, ligand design, and optimisation
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ResearchCoffee pods and 3D printing combine to create cheap and quick Covid-19 tests
Repurposed aluminium capsules enable a point-of-care test ideal for remote and low-income settings
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ResearchIngestible COF that delivers insulin could help diabetics duck injections
When blood glucose levels are high, glucose displaces insulin loaded in the framework
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ResearchMachine learning tool sets out to find new antimicrobial peptides
IBM researchers say their fully automated AI-driven system could speed up the discovery of molecules for novel antibiotics
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ArticleDigital technologies in the personalised medicines revolution
The revolution will be digitalised
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ArticleUnlocking the future of medicines manufacturing with digital innovations
The Medicines Manufacturing Innovation Centre promises to revolutionise how we formulate, trial and produce medicines
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BusinessAntibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
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OpinionHow the pandemic might change drug research
Derek Lowe muses on some positive lessons learned
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BusinessWhy manufacturing Covid vaccines at scale is hard
Exploring the pinch points vaccine makers face as they ramp up production
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ResearchMolecular pendulum sensors could track and monitor disease
DNA–antibody probes can detect specific proteins inside a live subject