Medicinal chemistry – Page 23
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ResearchCoffee pods and 3D printing combine to create cheap and quick Covid-19 tests
Repurposed aluminium capsules enable a point-of-care test ideal for remote and low-income settings
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ResearchIngestible COF that delivers insulin could help diabetics duck injections
When blood glucose levels are high, glucose displaces insulin loaded in the framework
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ResearchMachine learning tool sets out to find new antimicrobial peptides
IBM researchers say their fully automated AI-driven system could speed up the discovery of molecules for novel antibiotics
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ArticleDigital technologies in the personalised medicines revolution
The revolution will be digitalised
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ArticleUnlocking the future of medicines manufacturing with digital innovations
The Medicines Manufacturing Innovation Centre promises to revolutionise how we formulate, trial and produce medicines
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BusinessAntibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
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OpinionHow the pandemic might change drug research
Derek Lowe muses on some positive lessons learned
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BusinessWhy manufacturing Covid vaccines at scale is hard
Exploring the pinch points vaccine makers face as they ramp up production
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ResearchMolecular pendulum sensors could track and monitor disease
DNA–antibody probes can detect specific proteins inside a live subject
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OpinionWhy are impurity regulations different for food and drugs?
The pharmaceutical and food industries should work together more closely on genotoxic impurities
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FeatureFlow chemistry surges forward
The long-discussed technique could help make pharma manufacturing more distributed, finds Andy Extance, and create opportunities for chemists with the right skills
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ReviewThe Doctor Who Fooled the World: Andrew Wakefield’s War on Vaccines
The story of the man who created the myth that a vaccine causes autism
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BusinessUniversity team’s silica coats stop vaccines spoiling at room temperature
Asel Sartbaeva hopes her pioneering ensilication technology will be adopted to store and transport pediatric vaccines to low-income countries
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NewsGreen light for world’s first Sars-CoV-2 studies that will infect healthy volunteers
UK trials will assess how well Covid-19 treatments work and if vaccines protect against new virus variants
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BusinessCoronavirus variants stymie success of monoclonal antibodies
Lab-made antibodies can treat and protect people from Covid-19 but are more likely to succeed when administered as a cocktail
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FeatureDrugging RNA
Some medicinal chemists have changed their focus from proteins to target RNA, finds Rachel Brazil
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WebinarPhysics-based computational modeling applied to the design and optimisation of biologics
Explore how FEP technology (including FEP+) can be applied in protein engineering work
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ReviewThe Poison Trials: Wonder Drugs, Experiment, and the Battle for Authority in Renaissance Science
An extremely well-researched monograph containing stories that bear an eerie resemblance to today’s politicised clinical trials
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ResearchLinking chemistry with surgery to detect cancerous cells in situ
Livia Schiavinato Eberlin explains how her team has developed a hand-held device for surgeons that analyses tissue samples on a mass spectrometer mid-operation