Medicinal chemistry – Page 24
-
ReviewSuperbugs: The Race to Stop an Epidemic
A doctor’s story about his fight against drug-resistant microbes that threaten the future of medicine
-
ResearchSpectroscopic biomarkers track Huntington’s disease progression
Analysis recognises biochemical changes that are unique to Huntington’s
-
ResearchEngineered insulin with enhanced thermal stability inspired by fish-hunting snails
Four-disulfide insulin has similar bioactivity to native human insulin
-
OpinionCleaning up chemical kitchens
In a busy plant, ensuring small changes don’t produce unforeseen toxic impurities is key
-
NewsEuropean commission gives green light to first Ebola vaccine
Drug shown to be effective and safe following clinical trials involving 16,000 people
-
ArticleArtificial intelligence: on the cusp of a digital revolution
AI is transforming the pharma industry and its drug discovery pipeline
-
ResearchFlow synthesis produces chiral intermediate for antidepressant drug
The first solvent-free organocatalytic flow process yields the key chiral intermediate for paroxetine on a multigram-scale
-
NewsSwipe right to help in the fight against Huntington’s disease
Citizen science project improves understanding of protein misfolding disorders like Huntington’s and Alzheimer’s diseases
-
FeatureSeparating turmeric fact from fiction
Thousands of papers have been published on curcumin’s healing potential, but its usefulness is not yet proven, finds Andy Extance
-
-
OpinionWill computers ever discover drugs from scratch?
With enough understanding and computing power, it should be possible, but will it happen?
-
WebinarAdvantages of characterising pharmaceuticals using DSC and TGA
Learn how APIs, excipients and formulations can be investigated by differential scanning calorimetry and thermogravimetric analysis
-
WebinarAI and deep learning for chemistry with Pipeline Pilot
Learn how teams can effectively collaborate, manage and implement machine learning using Pipeline Pilot from Dassault Systèmes
-
NewsStudy claiming gene-edited babies were more likely to die young was wrong
Database bias introduced major error in a now retracted study on Crispr babies’ mortality
-
PodcastHypoxia-inducible factors – HIFs
The oxygen sensors that help life react to changing conditions, key to the 2019 Nobel prize in physiology or medicine
-
BusinessThe rise of venture philanthropy
More and more charities are investing in companies, and looking for returns on that investment, as an alternative to traditional grants
-
PodcastCiguatoxin
The toxin found in reef fish that leads to food poisoning so bad it can cause life-long symptoms
-
RSCThe future of chemistry: Science Horizons and Chemistry Means Business
Hundreds of scientists contributed to the Royal Society of Chemistry’s Science Horizons report to build a picture of the challenges and opportunities the next generation will bring
-
ResearchAlzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
-
ResearchMetallohelices emulate antimicrobial peptides
Scientists move away from traditional drug candidates to evade resistance