Medicinal chemistry – Page 27
-
NewsExplainer: how is the vaccine pipeline for Covid-19 looking?
The race to develop a vaccine is almost six months old. Who’s in the lead?
-
PodcastDexamethasone
News that this cheap, ubiquitous steroid drug may reduce deaths in Covid-19 cases has been greeted with cautious optimism
-
NewsCovid-19 is forcing pharma to rethink clinical trials
Drug trials have become a casualty of Covid-19, but the pandemic is also prompting change
-
OpinionMaking the right call on dexamethasone
The way we do things in research has to change in life or death situations
-
WebinarWL Gore: Optimising production processes with Design of Experiments
Learn how WL Gore use definitive screening designs to analyse multiple factors and optimise production processes
-
ResearchUnprecedented biosynthetic transformation found to connect antibacterial polyketides from ant microbiome
Study identifies enzymes that convert flat fasamycins into three-dimensional formicamycins
-
ResearchAlgorithm devises synthetic contingency plans for Covid-19 drug
Retrosynthesis software tool can identify multiple synthetic routes that use inexpensive and diverse starting materials while avoiding patented methods
-
NewsCaution urged as scientists await results of trial that finds steroid cuts Covid-19 deaths
Claims that 60-year-old drug dexamethasone dramatically lowers fatality rate of seriously ill Covid-19 patients await peer review
-
FeatureThe difficulties of drugging our brains
Following the withdrawal of many large pharma companies from central nervous system research, Andy Extance finds new drug development patterns are emerging
-
PodcastCimetidine
Mike Freemantle introduces the peptic ulcer treatment cimetidine, which – as Tagamet – became the first blockbuster drug
-
ResearchMethod that yields oxygen-18-enriched alcohols set to bolster drug studies
Mitsunobu-based protocol is simple alternative to limited and lengthy methods
-
OpinionCollaboration is key to AI-aided drug discovery
The AI Cures project shows how artificial intelligence can assist the search for a cure for Covid-19
-
ResearchRespiratory viruses detected in 30 minutes with the help of a smartphone
$50 smartphone accessory could be adapted for Covid-19
-
BusinessDeveloping antiviral mask technology in a pandemic
Surface chemistry strategies play a pivotal role in personal protective equipment that can neutralise the Sars-CoV-2 virus
-
ArticleOptimising biotech processes
Fujifilm Diosynth Biotechnologies achieve both speed and scale through designed experiments
-
PodcastFexinidazole
The World Health Organisation hope to eradicate sleeping sickness within our lifetimes. Jamie Durrani looks at a drug that may make it possible.
-
ResearchDatabase offers another way to search for drugs – by activity not structure
Dataset offers new way for biomedical researchers to identify potential drug candidates
-
FeatureDrugging the gut microbiome
Treating the bacteria that live inside us can improve our own health. Clare Sansom meets our tiny friends
-
WebinarTeaching Design of Experiments to chemists: lessons from Imperial College London
First-hand experience from Imperial College London: Join us to learn about the importance and efficient implementation of a DoE training program in chemistry
-
OpinionCovid-19 poses trust issues for science
The pandemic is proving the importance of public trust in science