Medicine and health – Page 12
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ResearchHepatitis C drug lead designed to target virus RNA
Gene-to-RNA-to-medicine pipeline possible thanks to technique that reveals interactions between RNA and small molecules
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ResearchGenentech antibiotic quells resistance
Modified arylomycin combines high potency with new mechanism of action
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ResearchBlood markers link firefighters' lung disease to WTC attacks
Firefighters who developed lung disease after responding to 11 September attacks in New York connected to specific metabolic profile
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ResearchBismuth drugs kill bacteria by disrupting metabolism
Scientists throw kitchen sink of omics techniques at understanding complicated response of prevalent human pathogen to bismuth drug
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ResearchMOF detox could save aspirin overdose patients
Detoxifying metal–organic framework removes dangerous doses of salicylic acid from rats’ guts
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ResearchArtificial intelligence seeks out new anticancer drugs
A combination of machine learning methods yields promising results for drug discovery
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ResearchAI tool could save on animal tests
Algorithm could also help unravel poisoning or environmental contamination cases
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ResearchFour step route to carbotricycles
Elegant strategy that directly assembles 5–8–5 scaffolds from simple precursors paves way to a new library of bioactive compounds
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ResearchTool to navigate chemical space aims to be ‘Google Maps of drugs’
Software allows links between 8000 drugs and 47,000 compounds of environmental concern to be explored in 3D
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ResearchScaffold could fill a gap in stroke therapy and help damaged brains recover
Bioactive filler could promote recovery in damaged regions
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ResearchSurgical sensor tracks healing and then simply fades away
Exceptionally sensitive biodegradable implant can sense strain and pressure on recovering tendons
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ResearchBrain chemistry hints at how obesity impairs antidepressants
Histamine released in response to obesity or bacterial toxins prevents benefits from SSRIs – and that drugs that target these inflammatory signals may restore them
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ResearchNew theory for why lithium helps bipolar patients
Molecular insight could help researchers design mood stabilisers with fewer side effects
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ResearchArtificial blood reaches the feline frontier
Space crystals of serum proteins help scientists make a red blood cell substitute for cats
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ResearchJelly implant keeps an eye on body oxygen levels
A soft hydrogel implant – the first of which has survived in the foot of its inventor for four years – could detect circulatory problems that end in amputations
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ResearchSolving the crystal maze
Workflow swaps gut feelings for data when designing continuous crystallisation processes
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ResearchBacteria churn out a million potential protein drugs
Modified bacteria produce enormous library of macrocycles, one of which inhibits a HIV protein
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ResearchTofu works as tissue-engineering scaffold
Garlic, ginger and chilli swapped for fibroblast cells
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ResearchAmerican Civil War era tea yields modern day medicine
Macrocyclisation strategy key to obtaining long known alkaloid with untapped potential
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ResearchAntimalarial plant's chlorophyll catalyses drug synthesis
New ‘green’ method makes malaria-fighting artemisinin’s synthesis faster and cheaper with industrial production planned for 2021