Organic chemistry – Page 15
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ResearchDoubly negative dianions can form π hole bonds too
Researchers report an attractive interaction between two doubly negative dianions for the first time
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ResearchRecord-breaking hexagon made out of fused aromatic rings
90 rings form the largest structure of its kind ever made
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ResearchDearomatisation, but without nasty reagents
New Birch reduction protocol creates solvated electrons without the dangerous combination of liquid ammonia and alkali metal
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ResearchAre organic chemists discovering fewer reactions than they were decades ago?
Analysis of millions of transformations reveals reliance on popular methods – and the rise of complex reactions
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ResearchPlasma-based approach leads to more reactive oxygen donors for alkene epoxidation
Yield of epoxidation reaction increased, and waste reduced, by using CO2-derived atomic oxygen and plasma-based conditions
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OpinionTaking the right inspiration from nature
Scientists need to be selective about their sources of inspiration
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ResearchClippanes join rotaxanes and catenanes in mechanically interlocked molecule family
Keck-clip molecules consist of two entangled gold–carbene metallotweezers
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ResearchFirst fundamentally new form of adsorption for more than 90 years driven by molecular machines
Unlike physisorption and chemisorption, the newly discovered ‘mechanisorption’ is an active process that can store energy or chemicals
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ResearchCooking oils work as solvents for metal-catalysed reactions
Suzuki–Miyaura, Hiyama, Stille, Sonogashira and Heck cross-couplings shown to proceed with quantitative yields in certain vegetable oils, fish oil, butter and waxes
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FeatureHow organocatalysis won the Nobel prize
Jamie Durrani tells the story of how two young upstarts, Ben List and David MacMillan, created a whole new field of catalysis
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ResearchExploiting evolution to explore chemical space shows promise for drug discovery
Using molecular trees – similar to family trees – chemists could predict how products will evolve to make new molecules
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ResearchMöbius metallacycles show their aromaticity with textbook reactivity
First electrophilic aromatic substitution reactions with unusual molecules
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ResearchExplainer: why has asymmetric organocatalysis won the chemistry Nobel prize?
In a rather unexpected move by the Nobel committee, this year’s prize in chemistry has been awarded to Benjamin List and David MacMillan
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NewsAsymmetric organocatalysis scoops 2021 chemistry Nobel prize
Benjamin List and David MacMillan recognised for research that makes chemistry greener
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ResearchPeptide superstructures speed up Michael reaction
A tripeptide that self-assembles into a supramolecular fibres accelerates an asymmetric benchmark reaction by up to 74%
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ResearchUltraphosphates break decades-old anti-branching rule
Discovery of elusive branched phosphates’ unexpected stability means they could have played a role in prebiotic chemistry
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ResearchMethod to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
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ResearchGiant molecular cage protects plastic-eating enzyme
Caged protein withstands temperatures much hotter than its usual melting point and becomes 1000 times more resistant to solvents
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ResearchEnantioselective synthesis of elusive chiral nitrogen compounds discovered by chance
An ‘elegant and simple’ way to make nitrogen stereocentres by supramolecular recognition