All Macrocycle articles
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ResearchDihydropyrazine-embedded macrocycles behave like supersized cycloalkanes
Giant molecular rings that mimic the puckered shapes of cyclobutane, cyclopentane and cyclohexane could offer new insights into conformational dynamics
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ResearchPillar[5]arene gets fully furnished with bulky aromatics
Synthesis developed by pillararene pioneers overcomes steric hindrance while preserving macrocycle’s pillar-shaped structure
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ResearchElusive crystals provide structural evidence of global aromaticity in a macrocyclic hydrocarbon
Reduced forms of [24]paracyclophanetetraene provide fresh understanding of redox-based aromaticity switching
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ResearchTetraquinoline is the newest member of the nitrogen macrocycle family
The new saddle-shaped macrocycle shows catalytic activity and affinity to zinc cations
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ResearchChemical Turing machine reads molecular tape
Crown ether ratchet reads out molecular strand’s chirality
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ResearchArtificially evolved enzyme tackles tricky cross coupling
Directed evolution on the metalloenzyme cytochrome P450 creates a catalyst for making macrocyclic antibiotics
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![Terphen[3]arene](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/100x67/7/3/6/518736_d2cc00040gf1_733670.jpg)
ResearchSulfonated macrocycle helps the medicine go down
A supramolecular approach makes alkaloid drugs taste less bitter
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OpinionA transition metal handyman
Using nickel templating to promote a large molecule for organic electronics
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ResearchIntroducing the tubulararenes, a new class of strained aromatic compounds
Electroactive container molecules built from the bottom-up
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ResearchMacrocycles slide freely across carbon nanotubes
Simulations suggest macrocycles show superlubricity at room temperature
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ResearchGiant tree molecule made out of 45 rotaxanes switches size on demand
Mechanically interlocked molecules give dendrimer the ability to expand and contract
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ResearchFirst molecular knots made from just benzene rings
Catenane and trefoil knot are the first mechanically interlocked molecules made from only carbon and hydrogen
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ResearchTriangle molecule charges up aluminium batteries
Cathode made from triangular macrocycle hosts complex metal cations in a rechargeable aluminium battery
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ResearchMacrocycles power up carbon nanotubes
Interlocked molecules tune the electronic properties of nanotubes, allowing researchers to control their catalytic activity
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ResearchRound-the-ring catalysis makes cyclic peptides chiral
Classic hydrogenation catalyst installs multiple stereocentres one by one to create small amino acid rings as single enantiomers
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ResearchBacteria churn out a million potential protein drugs
Modified bacteria produce enormous library of macrocycles, one of which inhibits a HIV protein
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ResearchMolecular box treats chemists to a strained surprise
Introducing pillar[4]pyridinium – the first of a new family of macrocycles
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ResearchRoute to fiendishly complex marine molecule cut in half
Shortcut to promising natural product already in Alzheimer’s and HIV trials
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ResearchMolecular suit provides basic protection
A removable macrocyclic suit can protect a small cation from strong bases