Medicinal chemistry – Page 30
-
-
BusinessSixth in a line of Alzheimer’s drugs fails in trials
Treatments designed to stop amyloid peptide formation all seem to cause cognitive impairment rather than prevent it
-
ArticleThe importance of solid form science in modern drug development
A recent study suggests that around 40% of drugs with market approval exhibit poor water solubility and although this is not a new problem, solutions like those offered by Johnson Matthey are still relevant to today’s pharma market
-
OpinionUnder a cloud
Chemical detective work is needed to track down what’s been killing e-cigarette users
-
ResearchElusive protein and key to many tropical diseases found after decades of searching
Discovery offers powerful new target to treat trypanosome parasite illnesses that affect millions
-
PodcastSodium fluoroacetate
The controversial killer compound – also known as 1080 – being used to protect New Zealand’s native wildlife
-
OpinionEmbracing structural disorder
Medicinal chemists need to overcome their fear of fuzzy proteins
-
NewsUS children’s hospital takes delivery of one of world’s most powerful NMR spectrometers
Instrument offers unprecedented opportunities to study disease development
-
NewsDeaths from vaping-linked lung disease in US connected to vitamin E additive
Tocopheryl acetate implicated in 380 cases of severe lung disease and six deaths
-
ReviewMescaline: A Global History of the First Psychedelic
A story about the people who harvested, used, abused, regulated and investigated the mind-altering drug
-
-
FeatureStem cell hype
Many clinics around the world offer unproven treatments, while genuine therapies are slowly making their way through trials. Anthony King reports
-
PodcastDomoic acid
The marine toxin that drives animals crazy and might have inspired one of Alfred Hitchcock’s most famous films
-
PodcastBoric acid
Mike Freemantle revisits battlefield surgery to investigate boric acid, a key part of Dakin's antiseptic solution used extensively in the first world war
-
ResearchRetrosynthetic algorithm broadened to design similar, but different, molecules
Chematica can now design efficient syntheses for large compound libraries
-
PodcastAmygdalin & Laetrile
Patrick Hughes delves into the molecule at the centre of a decades-old cancer treatment conspiracy theory
-
ResearchWood microfluidics carve out a niche
Teflon-coated wood devices perform as well as plastic equivalents but face some challenges before they can realise their clinical and sustainable potential
-
NewsConcerns raised over ‘regrettable’ BPA substitutions
Research indicates chemicals used as alternatives to bisphenol A in polycarbonate plastics and epoxy resins aren’t always safer
-
NewsData manipulation casts shadows on Novartis gene therapy
Manufacturing problems with other new medicines highlight difficulty of developing advanced treatments
-
OpinionMargaret Brimble: 'Spiroketals are my favourite molecules'
The New Zealand chemist on careers, creativity and why everything just has to be blue