Medicinal chemistry – Page 31
-
ResearchTotal synthesis of H. pylori antigen creates starting point for gastric cancer vaccine
Remote participation strategy helps chemists make sterically-congested repeating fragment
-
FeatureCan smart biomaterials deliver?
James Mitchell Crow explores the next generation of therapeutic biomaterials, which aim to interact dynamically with the body and help to control diabetes and heal wounds
-
PodcastIminosugars
After some promising results treating ill pets, some researchers think iminosugars could become treatments for infection and even cancer. Mike Freemantle explores the buzz around iminohoney
-
BusinessPharmaceuticals roundup 2019
Under the shadow of political turmoil and major lawsuits, the industry returned to its strengths – making new drugs, and finding new ways to do it better
-
PodcastOxycodone and hydrocodone
Frances Addison examines how our quest to control and manage pain has led to a modern medical crisis, as opioids oxycodone and hydrocodone are among the most abused prescription medications in the US
-
ReviewSuperbugs: The Race to Stop an Epidemic
A doctor’s story about his fight against drug-resistant microbes that threaten the future of medicine
-
ResearchSpectroscopic biomarkers track Huntington’s disease progression
Analysis recognises biochemical changes that are unique to Huntington’s
-
ResearchEngineered insulin with enhanced thermal stability inspired by fish-hunting snails
Four-disulfide insulin has similar bioactivity to native human insulin
-
OpinionCleaning up chemical kitchens
In a busy plant, ensuring small changes don’t produce unforeseen toxic impurities is key
-
NewsEuropean commission gives green light to first Ebola vaccine
Drug shown to be effective and safe following clinical trials involving 16,000 people
-
ArticleArtificial intelligence: on the cusp of a digital revolution
AI is transforming the pharma industry and its drug discovery pipeline
-
ResearchFlow synthesis produces chiral intermediate for antidepressant drug
The first solvent-free organocatalytic flow process yields the key chiral intermediate for paroxetine on a multigram-scale
-
NewsSwipe right to help in the fight against Huntington’s disease
Citizen science project improves understanding of protein misfolding disorders like Huntington’s and Alzheimer’s diseases
-
FeatureSeparating turmeric fact from fiction
Thousands of papers have been published on curcumin’s healing potential, but its usefulness is not yet proven, finds Andy Extance
-
-
OpinionWill computers ever discover drugs from scratch?
With enough understanding and computing power, it should be possible, but will it happen?
-
WebinarAdvantages of characterising pharmaceuticals using DSC and TGA
Learn how APIs, excipients and formulations can be investigated by differential scanning calorimetry and thermogravimetric analysis
-
WebinarAI and deep learning for chemistry with Pipeline Pilot
Learn how teams can effectively collaborate, manage and implement machine learning using Pipeline Pilot from Dassault Systèmes
-
NewsStudy claiming gene-edited babies were more likely to die young was wrong
Database bias introduced major error in a now retracted study on Crispr babies’ mortality
-
PodcastHypoxia-inducible factors – HIFs
The oxygen sensors that help life react to changing conditions, key to the 2019 Nobel prize in physiology or medicine