Medicinal chemistry – Page 35
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ResearchWearable sensor checks blood alcohol content using sweat
Device shows how sweat could be used as a non-invasive source of biochemical information
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BusinessBreaking the silence of RNA interference drugs
A wave of treatments is set to follow the first approval of an RNAi therapy
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ResearchScorpion venom peptide engineered to sting brain disorders
Structure used to escort nanoparticles across blood–brain barrier also resists protease degradation
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ReviewBitter Pills: The Global War on Counterfeit Drugs
Muhammad Zaman’s book gives an account of the challenges facing drug regulators worldwide
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BusinessTransforming PET imaging with silicon
Fuzionaire Diagnostics can add Si–18F radiolabels to a variety of molecules quickly, easily and cheaply
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ReviewHow to Change Your Mind: The New Science of Psychedelics
Journalist Michael Pollan’s 9th book is a fascinating history of psychedelic drugs.
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ResearchHidden gene cluster unearthed to reveal antibacterial natural product
Scientists encourage soil microorganisms to express themselves
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PodcastFuranocoumarin
Florence Schechter discovers how a seemingly healthy grapefruit-based breakfast could disrupt your daily drugs
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ResearchFirst oral antibiotic booster for four decades could tackle drug resistance
Sulfate-masking strategy makes bacterial enzyme inhibitor an easy pill to swallow
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ResearchDeep tissue penetration allows fluorophore to guide tumour surgery
Bioimaging probe excited by longer wavelengths of light but doesn’t suffer from long-term retention in the immune system
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OpinionPassing through checkpoints
A new breed of cancer treatments highlights what’s possible when industry concentrates its efforts
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ResearchNew peptide destroys Zika virus in brain for first time
Engineered molecule ruptures virus particles to tackle infection
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OpinionThe potential of promiscuity
Nobel recognition for a concept whose benefit to humankind is far from being truly realised
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ResearchMilk protein could alleviate metallic taste following chemotherapy
Study indicates that a lactoferrin supplement could treat taste and smell irregularities experienced by cancer patients
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BusinessCancer immunotherapy spreads rapidly
New approvals and expanded use for checkpoint inhibitor drugs illustrate the power of Nobel-winning science
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ResearchNanopore sensors make breakthrough in monitoring health and disease
Biosensor simultaneously measures metabolite biomarkers in bodily fluids
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FeatureHow chemical evolution took the 2018 chemistry Nobel prize
Emma Stoye has the full story of how Frances Arnold, George Smith and Greg Winter put evolution to work in the lab
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OpinionThe projects drug companies wish they’d never started
Failures are common in drug research, but some are bigger than others
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