Medicinal chemistry – Page 35
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ResearchNeonicotinoid exposure could be harming mammals
Deer study suggests the toxic effects of these pesticides may not be limited to insects
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BusinessBuilding a biological biocide
Aqualution Systems produces stable hypochlorous acid, a natural biocide up to 300 times more effective than bleach
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ResearchSynthetic enzyme wipes out tough bacterial biofilms
After success in mice strategy could be an alternative to antibiotics to treat wounds
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NewsAsthmatics encouraged to switch to lower carbon footprint inhalers
The majority of inhalers prescribed in UK contain a potent greenhouse gas
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NewsWhy jury verdicts get overruled in US industry cancer trials
Judges often end up intervening post-trial in complex cases with conflicting scientific evidence
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NewsLettuce could be used to grow drugs on Mars
Infecting plants with a bacterium that can genetically modify plants could be an answer to producing drugs on other planets
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ResearchDroplet screening set to accelerate immunotherapies into the clinic
Single-cell technique eliminates inefficiencies when identifying immune cells active against specific cancers
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ResearchCo-crystals fish out cannabinoid from plant extract
Purifying cannabidiol from natural cannabis extract made cheap and easy thanks to amino acid partner
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BusinessNurturing the next biotech generation
As incubator environments evolve, options for new companies looking for support are broadening
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ResearchNew family of peptides from extremophile show antibiotic promise
Scientists isolate salinipeptins from a bacterium living in America’s Dead Sea
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ArticleSmall particles making a big splash in clinical development
Nanoform is investigating how to tackle clinical attrition rates through nanonisation of APIs
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ArticleInvestigating multi-dimensional problems in drug substance development
Finding solutions to the biggest challenges faced during drug substance development relies on properly integrating analytical and production expertise
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ResearchHole-punching antifungal used as molecular prosthesis for cystic fibrosis
Drug creates artificial ion channels that could replace broken version in cystic fibrosis patients’ lung cells
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PodcastVinblastine and vincristine: Vinca alkaloids
Kat Arney unearths a story of an overlooked female researcher in the search for the origins of cancer drugs found in plants
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ResearchCopper mixes with alcohol abuse drug for anticancer action
Chemical model reveals how alcoholism drug disulfiram joins copper to kill cancer cells with oxidation overload
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ResearchSmall molecule finds flu virus’s weak spot
Drug candidate that targets highly conserved region of virus gave mice complete protection from swine flu
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FeatureThe battle to lose weight
Losing weight – and not putting it back on – is about much more than willpower. Nina Notman reports on the drugs trying to penetrate the complex metabolic web of hunger and satiety.