Medicinal chemistry – Page 51
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NewsUS urged to curb chemicals that harm brain development
NIH-backed coalition calls for immediate action to reduce developmental toxicant exposures
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ResearchTurbocharged synthesis makes antiviral Tamiflu in an hour
Production process showcases how organocatalysis can combine reactions in a single pot
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ResearchGold nanoclusters offer route to better vaccines
New technique improves immune response and safety of hepatitis E vaccine
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PodcastThiomersal
Kat Arney introduces the organomercury preservative associated with the current controversy around vaccines
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OpinionWe need a global plan to beat resistance
We all need to do our bit and act for the common good if we’re going to protect antibiotics
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NewsHigher lead levels in blood of Flint’s young children
US Centers for Disease Control and Prevention reports levels of lead are of concern
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ResearchMiniature carbon bottles hold promise as nano-reactors
Nanobubbles with hydrophobic interiors also have potential as drug delivery agents
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OpinionLinked data is the future for medicinal chemistry
Paul Groth explains why linked data is starting to revolutionise medicinal chemistry
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ResearchMirror-image trick yields real hits from a virtual chemical library
Scientists use mirror-image protein to identify potential new drugs from a previously unexplored library of natural product enantiomers
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Feature2Heavy drugs gaining momentum
With the first approval of a drug containing deuterium looking imminent, Nina Notman surveys the deuterated drug landscape
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News
New biobank supports Obama’s personalised medicine initiative
Mayo Clinic receives $142 million to shed light on individual differences in health and disease
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NewsWorld faces tough challenge turning words into action on antibiotic resistance
Countries are waking up to the challenge of ‘superbugs’ but agreeing a way forward will be tricky
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ResearchChemical synthesis injects new life into old antibiotics
Approach can construct wide range of new antibiotic candidates from simple chemical building blocks
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News
Large HIV vaccine trial to launch in South Africa
US funding agency will enlist 5400 people for HIV vaccine study in South Africa in November
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NewsInsider trading scandal topples head of Taiwan’s top research body
President of umbrella organisation overseeing 24 research institutions caught up in investigation into offloading of biotech shares prior to poor results
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PodcastTetraethyl lead
For decades, automobile fuel had a dangerous additive: Tetraethyl lead. Matt Gunther explains why a toxic compound was added to our fuel
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PodcastHaloperidol
It failed as a painkiller, but Haldol rapidly became an essential medicine for schizophrenia. Raychelle Burks explains more
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NewsLack of data on BPA exposure in developing countries
Few studies focus on developing countries where regulations around BPA use are less strict
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OpinionWhy we need an allergic reaction
Michael Walker calls for a grand vision to protect people with food allergy
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OpinionCan we wait for e-cigarette trials?
Safety data is needed but is not a reason to ignore vaping now, says Thomas Hartung