Medicinal chemistry – Page 49
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ResearchPersonalised medicine boost as cancer drug monitored in real-time
Aptamer-based sensors can track levels of small molecules in rats as the go about their business
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BusinessTaming vaccines with chemistry
Vaxxilon aims to simplify vaccine development by replacing biological components with well-defined synthetic molecules
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ResearchAncient whirligig toy inspires cheap, modern centrifuge
People-powered centrifuge can separate blood samples in minutes
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NewsFears that gene-editing cancer trials are premature
Warnings from geneticists that Crispr trial failures could knock promising technique’s prospects
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ResearchRoadkill: new molecules at the side of the road
Wild animals run down on the roads can open surprising doors for opportunistic biochemists
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FeatureNew opioid drugs
Creating powerful new painkillers is a constant battle against side-effects – particularly addictions. James Mitchell Crow reports
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FeatureIntracellular delivery
Drugs that can enter cells and take useful payloads with them are maturing, finds Andy Extance
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ResearchChemoluminescent nanoparticles detect multiple deadly viruses in one go
A detection system can test for multiple viruses in one sample
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ResearchDiamonds to track down origins of diseases of ageing
Fluorescent nanodiamonds reveal the inner workings of neurons
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OpinionHow much does fashion influence chemists?
Is that new reaction the next Nobel-worthy breakthrough, or just a flash in the pan?
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PodcastBromodeoxyuridine
Kat Arney illuminates the story of a molecular ‘highlighter pen’ for growing cells
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OpinionRestarting the mental health pipeline
The lack of UK investment in new drugs for mental health disorders is a problem – but the tide may be about to turn
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CareersThe trials and tribulations of drug discovery
The many pitfalls medicinal chemists face when creating a new drug
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ResearchPoison dart frog toxin made in mirror image
Toxin’s non-natural enantiomer offers new tool to probe nerve disorders