Medicinal chemistry – Page 54
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NewsPoor diagnostics hinder battle against antibiotic resistance
Healthcare workers’ tools to diagnose infections remain stuck in the past
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NewsMalaria vaccine pilot studies recommended by WHO
GlaxoSmithKline’s RTS,S vaccine must undergo further testing before being rolled out, says World Health Organization panel
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ResearchTramadol found in African soils almost certainly artificial
New evidence may end speculation over plant production of painkiller first synthesised in the 1960s
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ResearchAdd more peroxide to stabilise new drug molecules
From a curiosity to life-saving medicine – how peroxides make for stable and efficient drugs
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ResearchCobalt could cut costs for pharma ingredients
Carboxylic acids and esters hydrogenated without the need for expensive precious metals
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PodcastCephalosporins
A story which starts knee-deep in sewage and ends with the spread of drug resistant infections like MRSA
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NewsCall for collaboration to take on resistance
Better partnerships across research, industry and policy are needed to tackle antimicrobial resistance, say research leaders
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NewsAntiparasitic drugs derived from natural products take 2015 medicine Nobel
Top science gong awarded for discovery and development of drugs that have improved the lives of millions
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PodcastA is for Arsenic by Kathryn Harkup – Book club
In the first of a brand new podcast series, we get together to discuss ‘A is for Arsenic: the poisons of Agatha Christie’
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OpinionSpice up your compounds
An occasional foray into uncharted territory is the hot sauce of medicinal chemistry, says Derek Lowe
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FeatureA new hope in HIV prevention
New microbicide products could turn the tide against Aids for women in Africa, reports Dinsa Sachan
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ResearchAntibiotics pit against bacterial biofilms
Simple electrochemical device to more realistically assess antibiotic performance
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FeatureOligonucleotide drugs step up
Structural innovations are overcoming oligonucleotide drugs’ historical flaws, discovers Andy Extance
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News
Pepsi sets limit on caramel colouring chemical
Firm establishes legal threshold for the caramel food colouring by-product 4-MEI that California lists as a carcinogen
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Opinion
A shot in the arm
Vaccines for diseases that afflict the world’s poorest offer an escape not only from disease but also from poverty
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NewsNIH backs natural products research
The US National Institutes of Health will fund new research centres investigating botanical supplements to the tune of $35M
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ResearchCheap and sensitive test for a key prostate cancer marker
Supramolecular-coated magnetic beads offer a cheap alternative to current early-stage monitoring techniques
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ResearchPurple bacteria signal zinc deficiency
Low-cost bacterial ‘litmus test’ could help identify nutrient-deficient populations