Labourers working at the construction site of a state highway road

Iran war’s global impact keeps growing

Shortages of bitumen, cooking gas and jet fuel are pushing up prices and disrupting construction

Open paint tins

Paint manufacturers still putting consumers at risk in Mexico with sale of toxic lead paints

Over half of paints sold in the country contain unsafe levels of lead pigments, with some reaching up to 29% lead

Firefighters

26 killed in fireworks factory explosion in China

Incident on 4 May injured over 60 others, with rescue work hampered by further fires and explosions 

OxyContin

Purdue Pharma’s opioid prosecution enables bankruptcy settlement

$5 billion criminal sentence paves the way for resolution of civil liabilities through bankruptcy court

Highlights

Two racing cars a comicbook style. One is racing for Team LFP and the other is for Team NMC

The battery chemistry race shaping the future of electric vehicles

Science and global politics intertwine in the rivalry between lithium nickel manganese cobalt oxides and lithium iron phosphate

A large LNG tanker ship in an industrial port. In the foreground are small pleasure boats.

Gulf chemicals supply disruption will continue for months to years

Impact on petrochemicals, fertilisers and various co-products like helium and sulfur will ripple throughout extensive supply chains

Rolled out raw cookie dough with three round cookies and their corresponding holes. There is a fourth round hole being cut out but the cookie cutter but the cookie is star-shaped.

The curious case of disappearing polymorphs

From crystallographers’ beards to billion-dollar lawsuits, the phenomenon of disappearing polymorphs has puzzled chemists for decades. Now researchers are finally unravelling the science behind why stable crystal forms suddenly vanish – and discovering how to bring them back

Trump silhouette

‘The truth is supremely valuable and we cannot lie our way to it’

As a scientist with family in Iran, Derek Lowe finds his own government’s approach to truth alarming

Parasites

Boron plays a key role in new sleeping sickness drug

Acoziborole is the first single-dose treatment for both early and late stage sleeping sickness

Labourers working at the construction site of a state highway road

Iran war’s global impact keeps growing

Shortages of bitumen, cooking gas and jet fuel are pushing up prices and disrupting construction

A close up of a person wearing a branded Polypure lab coat holding a test tube of pale blue liquid

Advantages of monodisperse PEG in drug development

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Precision matters: why monodisperse PEG is transforming drug development.

OxyContin

Purdue Pharma’s opioid prosecution enables bankruptcy settlement

$5 billion criminal sentence paves the way for resolution of civil liabilities through bankruptcy court

Christian Hackenberger

‘Basic research is needed more than anything else’

Christian Hackenberger, co-founder of Tubulis, is excited that his team’s initial research is now creating clinical impact

Open paint tins

Paint manufacturers still putting consumers at risk in Mexico with sale of toxic lead paints

Over half of paints sold in the country contain unsafe levels of lead pigments, with some reaching up to 29% lead

26 killed in fireworks factory explosion in China

Incident on 4 May injured over 60 others, with rescue work hampered by further fires and explosions 

Thousands of tonnes of hazardous chemicals entered environment due to EU delays

Report claims stalled roadmap has slowed phase-out of flame retardants, bisphenols and other chemicals

Purdue Pharma’s opioid prosecution enables bankruptcy settlement

$5 billion criminal sentence paves the way for resolution of civil liabilities through bankruptcy court

Major drug regulators advancing routes to reduce animal testing

US, UK and EU all have goals to eliminate animal testing

Fatal incident at US catalyst refiner under investigation

Two dead and 21 injured at silver reclamation facility after chemical mixture released hydrogen sulfide

Patches

World first for clinical trial of skin patch to monitor therapeutic drugs in real time

Sensor could soon help doctors to prevent overdoses of drugs

Eco plant

Global analysis identifies trends in platform chemical research

Ammonia and methanol lead shift towards greener technologies

Fischer-Tropsch facility

Suppressing side reactions brings efficiency boosts for Fischer-Tropsch synthesis

Two new strategies tackle Fischer–Tropsch’s problematic side reactions

This fragment-based drug discovery library is designed to be sociable

Study targets a key bottleneck in hit to lead optimisation by designing fragments that are both structurally diverse and easy to elaborate

All stirred up: chemical engineers refute claims that ‘stirring doesn’t matter’

Failing to mix reactions in heterogeneous or industrial systems could cause numerous issues and might even be dangerous, preprint claims

Unrecovered byproducts from US mines could meet the country’s demand for dozens of critical materials

Huge quantities of metals and other elements are discarded each year in mining waste

Ten years on, pharma industry still testing for implausible alkyl sulfonate ester contaminants

Risk assessment for potential mutagenic side-products is still required by regulatory bodies, despite lack of evidence they form during drug production

Polymer membrane separates hydrocarbons, offering alternative to distillation

Microporous membrane enables energy efficient chemical separations

Labourers working at the construction site of a state highway road

Iran war’s global impact keeps growing

Shortages of bitumen, cooking gas and jet fuel are pushing up prices and disrupting construction

A large LNG tanker ship in an industrial port. In the foreground are small pleasure boats.

Gulf chemicals supply disruption will continue for months to years

Impact on petrochemicals, fertilisers and various co-products like helium and sulfur will ripple throughout extensive supply chains

Labourers working at the construction site of a state highway road

Iran war’s global impact keeps growing

Shortages of bitumen, cooking gas and jet fuel are pushing up prices and disrupting construction

A large LNG tanker ship in an industrial port. In the foreground are small pleasure boats.

Gulf chemicals supply disruption will continue for months to years

Impact on petrochemicals, fertilisers and various co-products like helium and sulfur will ripple throughout extensive supply chains

Labourers working at the construction site of a state highway road

Iran war’s global impact keeps growing

Shortages of bitumen, cooking gas and jet fuel are pushing up prices and disrupting construction

Paint manufacturers still putting consumers at risk in Mexico with sale of toxic lead paints

Over half of paints sold in the country contain unsafe levels of lead pigments, with some reaching up to 29% lead

26 killed in fireworks factory explosion in China

Incident on 4 May injured over 60 others, with rescue work hampered by further fires and explosions 

Major drug regulators advancing routes to reduce animal testing

US, UK and EU all have goals to eliminate animal testing

Fatal incident at US catalyst refiner under investigation

Two dead and 21 injured at silver reclamation facility after chemical mixture released hydrogen sulfide

Bursting bubbles break down PFAS

Mantisonix is using ultrasound to destroy fluorochemical pollutants in water

Christian Hackenberger

‘Basic research is needed more than anything else’

Christian Hackenberger, co-founder of Tubulis, is excited that his team’s initial research is now creating clinical impact

Geleen Netherlands

Sabic offloads petrochemicals and plastics plants in Europe and Americas

German private equity firms Aequita and Mutares aim to return struggling plants to profitability

Trump and leaders

Pharmaceuticals roundup 2025

Policy swings have made it a slippery year for pharma

Construction equipment

Chemicals industry roundup 2025

Europe hit hard by China’s independence push, but India is growing

3D ball and stick diagram of Tert-butyllithium-tetramer

Novel non-pyrophoric organolithiums for synthesis

Sponsored by

New, improved formulations of frequently used organolithium reagents that improve on safety, prevent pyrophoric reactions and improve shelf life

Chemical diagram showing the general formula for (NHC-H)₂Pd₂Cl₆ palladium complexes with a list of substituent variants, and two molecular models of (IPr-H)₂Pd₂Cl₆: one ball-and-stick and one wireframe representation.

Optimise cross-coupling with ligand-free NHC–Pd precatalysts

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Discover how new NHC–Pd precatalysts deliver superior performance without stabilising ligands

Thermal ellipsoid plot of the AdQPhos ligand

AdQPhos: Exceptional performance in α‑arylation reactions

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Download now to discover a more efficient and greener palladium cross-coupling catalyst