Biochemistry – Page 12
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PodcastVinblastine and vincristine: Vinca alkaloids
Kat Arney unearths a story of an overlooked female researcher in the search for the origins of cancer drugs found in plants
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ResearchCopper mixes with alcohol abuse drug for anticancer action
Chemical model reveals how alcoholism drug disulfiram joins copper to kill cancer cells with oxidation overload
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ResearchGenes that make lemons sour revealed
When life gives you lemons, mutate their proton pumps to make them sweeter
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PodcastFerrous sulfate
The iron compound that has been turning oak gall extract into indelible ink for centuries, but is now eating though our ancient manuscripts and musical scores
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ResearchGenetically engineered yeast brews up heady mix of natural and unnatural cannabinoids
Biotech yeast makes low-cost, high-quality THC and CBD – and cannabinoids never seen before – without growing cannabis plants
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Research‘Predator particles’ give mice infrared vision
Upconversion nanoparticles that bind to rods and cones shift invisible light to look green
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ResearchCarbon-fixing enzyme 10 times more abundant than previously thought
Calculations conclude there are 0.7 billion tonnes of rubisco in the world, an order or magnitude more than past estimates
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PodcastNitrogenase
The mysterious enzyme that can beat the world’s biggest chemical process when it comes to breaking the dinitrogen triple bond
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PodcastMelarsoprol
Cases of sleeping sickness – human African trypanosomiasis – are in decline, dropping 86% in Africa between 2000 and 2014. Gege Li explores the role that this toxic, arsenic-based medication has to play.
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PodcastOmega-3 fatty acids
Many consume cod liver oil due to 'a vague sense we should be taking them for something' – but what to the omega-3 fatty acids actually do?
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ResearchAlzheimer’s linked to infection of the brain by gum disease bacterium
Drug firm is developing treatment to inhibit bacterial enzymes believed to be damaging important protein
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ResearchSynthetic molecules fold up into abiotic proteins
Compound that self-assembles into giant folded ring could help scientists design bespoke abiotic proteins
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PodcastGene Machine by Venkatraman ‘Venki’ Ramakrishnan – Book club
2009 Nobel prize winner Venki Ramakrishnan takes us on a personal and professional journey to uncover the secrets of the ribosome
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ResearchDrug precursor made by solar-powered cyborg yeast
Indium phosphide nanoparticles supply electrons for shikimic acid synthesis
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ResearchTuring patterns explain shark scale development
The tooth-like scales on a shark’s skin show signs of reaction-diffusion molecular patterns, like human hair and chicken feathers
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PodcastLevulinic acid
How one footballer's climate concerns led to the creation of a green chemistry company: the story of Mathieu Flamini, GFBiochemicals and levulinic acid.
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PodcastFuranocoumarin
Florence Schechter discovers how a seemingly healthy grapefruit-based breakfast could disrupt your daily drugs
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PodcastPhenolphthalein
Kat Arney gets to the bottom of the story of phenolphthalein – a chemical with two very different uses. If you've measured pH in a classroom or had some trouble in the bathroom, you may have met this compound before.
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ResearchEnzyme ancestors resurrected to boost thermal stability
Scientists constructing enzyme library make serendipitous discovery