Biochemistry – Page 12
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PodcastPhenolphthalein
Kat Arney gets to the bottom of the story of phenolphthalein – a chemical with two very different uses. If you've measured pH in a classroom or had some trouble in the bathroom, you may have met this compound before.
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ResearchEnzyme ancestors resurrected to boost thermal stability
Scientists constructing enzyme library make serendipitous discovery
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OpinionThe potential of promiscuity
Nobel recognition for a concept whose benefit to humankind is far from being truly realised
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PodcastCaryophyllene
A biologically active compound from the biblical balm of Gilead, said to ‘heal the sin-sick soul’ and mentioned at the marriage of Prince Harry and Meghan Markle
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FeatureHow chemical evolution took the 2018 chemistry Nobel prize
Emma Stoye has the full story of how Frances Arnold, George Smith and Greg Winter put evolution to work in the lab
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NewsImmune-stimulating cancer treatment takes 2018 medicine Nobel
James Allison and Tasuku Honjo receive science’s highest honour for discovering how cancer stops immune cells from attacking
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ResearchGold rush for lignin conversion
Catalytic breakthrough surrounding the notoriously difficult oxidative depolymerisation of lignin could make cellulosic ethanol biofuels commercially viable
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![Designed heme-[4Fe-4S] metalloenzyme](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/100x67/8/8/5/138885_heme_index_2.jpg)
ResearchArtificial iron–sulfur catalyst is highly functional
Sulfite reductase mimic represents major advancement in engineering synthetic enzymes
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PodcastAntihistamines
From calming a hyperactive immune system to increasing cognitive abilities, these small molecules have a big impact
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ResearchNovel fatty acids have exceptional lubricant potential
Chinese oilseed plant offers opportunities for industry
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ResearchTwisting molecule probes cell membrane tension
Changing fluorescence visualises strain in live cells, and reveals unusual behaviour
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ResearchNerve agents destroyed by self-powering enzyme nanobot
Pumping action of tethered organophosphorus acid anhydrase as it breaks up sarin and Soman is used to release antidote
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ResearchPrebiotically plausible version of pH gradient generating catalyst
Scientists create simple metal ion system could have facilitated early metabolic processes, like ATP synthesis
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NewsWhat the ECJ ruling means for gene editing
The European Court of Justice has found Crispr-modified crops are subject to GMO regulations
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ResearchSupramolecular system refines enzyme impression
Metalloenzyme mimic combines a guest binding pocket, a well-defined coordination sphere and an internal base to achieve impressive catalytic control