Drug discovery and development – Page 25
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ArticlePlatinum metal complexes in medicine
The history of cisplatin, the drug that is still the gold – or should that be platinum? – standard in cancer drugs
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ArticleBiosensors, wearables and virtual biotech
In a world that is racing ahead with new technologies, has the drug development process distanced itself from the patients it ultimately provides for?
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ArticleWhy biocatalysis is so on trend
Biocatalysis has come a long way from just beer – there’s an enzyme for nearly everything
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ArticleThe ever-increasing attraction of biologics
Biologics promise targeted treatments for a range of conditions – if we can overcome the technological challenges
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FeatureThe antibiotic countdown
Where are the next generation of antibiotics going to come from? Clare Sansom looks at the pipeline
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ResearchAntimalarial plant's chlorophyll catalyses drug synthesis
New ‘green’ method makes malaria-fighting artemisinin’s synthesis faster and cheaper with industrial production planned for 2021
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NewsIllegal antibiotic combinations threaten efforts to battle antimicrobial resistance
Unapproved formulations make up two-thirds of combination therapies sold in India
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ResearchAntibiotic analogue puts researchers on path to ending herbicide drought
Research flags DNA gyrase as a new target for pesticides
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ResearchSoil search unearths new class of antibiotics
Malacidins have a novel mode of action and can kill MRSA
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BusinessCelgene takes a punt on M&A
Cancer specialist bags Juno therapeutics and Impact Biomedicines
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BusinessFDA new drug approvals more than doubled in 2017
The FDA approved 46 new drugs last year – the highest number in over two decades – due to factors like streamlined policies at the agency
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NewsChanging political climate threatens US cannabis research
Trump administration reverses rule protecting states with legalised marijuana
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BusinessDementia slips down pharma agenda
Pfizer, Shire, Acorda and Axovant rethink their neuroscience strategies
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ResearchSuzuki–Miyaura–hydrogenation targets 3D drugs
Researchers design a new pathway to make sp3 enriched drug molecules
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BusinessPharmaceuticals roundup 2017
Political influence has strongly shaped industry activity in the past year
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BusinessSanofi ordered to pull dengue vaccine
Philippines wants French drugmaker to cover immunisation program costs
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OpinionChanging the reproducibility rulebook
It pays to know when taking shortcuts is acceptable, and which it’s safe to take
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FeatureStaying one step ahead of the game
Clare Sansom examines the need for agile drug development when tackling emerging viral disease outbreaks
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BusinessGSK’s shingles vaccine gets thumbs up in North America
Inoculation slated to be a blockbuster
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OpinionNatural selection
Bioactive compounds don’t just inspire new synthetic strategies, they’re also the ultimate test