Medicinal chemistry – Page 39
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ResearchSelf-powered cancer therapy triple whammy
Diagnosis, drug delivery and effectiveness monitoring combination could realise precision cancer therapy
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ResearchDouble umpolung approach to amino amide synthesis
Unusual disconnection strategy behind stereocontrolled route to β-amino amides
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ResearchFluorinated compounds in cosmetic products
Moisturisers, shaving foam and foundation investigated as sources of per- and polyfluoroalkyl substances
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ResearchErythropoietin benefits from controlled sugar-coating
Click chemistry allows glycosylation at virtually any synthetic stage
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BusinessSartan drug contamination brings cancer uncertainty
Levels of nitrosamines and other carcinogens in affected tablets of valsartan and related drugs similar to smoking 20 cigarettes a day
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NewsX-ray crystallographer to oversee Rosalind Franklin Institute
Structural biologist James Naismith to become first director of UK’s new national life sciences institute
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ResearchWearable sensor checks blood alcohol content using sweat
Device shows how sweat could be used as a non-invasive source of biochemical information
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BusinessBreaking the silence of RNA interference drugs
A wave of treatments is set to follow the first approval of an RNAi therapy
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ResearchScorpion venom peptide engineered to sting brain disorders
Structure used to escort nanoparticles across blood–brain barrier also resists protease degradation
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ReviewBitter Pills: The Global War on Counterfeit Drugs
Muhammad Zaman’s book gives an account of the challenges facing drug regulators worldwide
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BusinessTransforming PET imaging with silicon
Fuzionaire Diagnostics can add Si–18F radiolabels to a variety of molecules quickly, easily and cheaply
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ReviewHow to Change Your Mind: The New Science of Psychedelics
Journalist Michael Pollan’s 9th book is a fascinating history of psychedelic drugs.
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ResearchHidden gene cluster unearthed to reveal antibacterial natural product
Scientists encourage soil microorganisms to express themselves
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PodcastFuranocoumarin
Florence Schechter discovers how a seemingly healthy grapefruit-based breakfast could disrupt your daily drugs
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ResearchFirst oral antibiotic booster for four decades could tackle drug resistance
Sulfate-masking strategy makes bacterial enzyme inhibitor an easy pill to swallow
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ResearchDeep tissue penetration allows fluorophore to guide tumour surgery
Bioimaging probe excited by longer wavelengths of light but doesn’t suffer from long-term retention in the immune system
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OpinionPassing through checkpoints
A new breed of cancer treatments highlights what’s possible when industry concentrates its efforts
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ResearchNew peptide destroys Zika virus in brain for first time
Engineered molecule ruptures virus particles to tackle infection
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OpinionThe potential of promiscuity
Nobel recognition for a concept whose benefit to humankind is far from being truly realised
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ResearchMilk protein could alleviate metallic taste following chemotherapy
Study indicates that a lactoferrin supplement could treat taste and smell irregularities experienced by cancer patients