Medicinal chemistry – Page 40
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BusinessVaccine scandal and heart drug recall show China’s pharma struggles
Fifteen arrests amid evidence of bribery related to vaccines, despite new standards and penalties for fraud
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BusinessNovartis exit from antibiotics a setback for race against resistance
Experts say business models must change to halt big pharma exodus
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ResearchArtificial intelligence seeks out new anticancer drugs
A combination of machine learning methods yields promising results for drug discovery
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ResearchAI tool could save on animal tests
Algorithm could also help unravel poisoning or environmental contamination cases
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BusinessTrump coaxes big promises from big pharma
Several drug industry giants are now pledging to freeze price increases in the US, but some suggest the movement is a publicity stunt or worse
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NewsNovichok poisoning breakthrough as original container found
Decontamination efforts continue as source of nerve agent found in victim’s house
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PodcastCannabidiol
The story of Charlotte Figi, Dravet syndrome and the cannabis compound controlling her condition
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Opinion'If I'd discovered metformin, I'd have tossed it aside...'
Trusting our intuition too strongly highlights how little we know about chemical activity
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PodcastUnthinkable by Helen Thomson – Book club
Helen Thomson looks at some of the rarest neurological conditions known to science
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NewsWHO gears up to solve the world’s antivenom crisis
Clinical trials planned to take on scourge of substandard, untested medicines
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ResearchFour step route to carbotricycles
Elegant strategy that directly assembles 5–8–5 scaffolds from simple precursors paves way to a new library of bioactive compounds
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ResearchTool to navigate chemical space aims to be ‘Google Maps of drugs’
Software allows links between 8000 drugs and 47,000 compounds of environmental concern to be explored in 3D
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NewsNew life sciences institute wants to make drug discovery 10 times more efficient
The UK’s £103 million Rosalind Franklin Institute will unite robotics, chemistry and biophysics to generate drug candidates within weeks
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NewsVaccines central to efforts to head off latest Ebola outbreak
Ring vaccination strategy could halt disease in its tracks provided health systems can cope
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OpinionThe three muses of scientific discovery
Inspiration, experimentation and happy accidents are all pathways to a breakthrough
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NewsWhy antibiotic pollution is a global threat
Rising antibiotic resistance caused by pollutants needs action
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ResearchSurgical sensor tracks healing and then simply fades away
Exceptionally sensitive biodegradable implant can sense strain and pressure on recovering tendons