Medicinal chemistry – Page 40
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NewsTracker to name and shame for failure to report clinical trial results
Developers of online tool hope that it will improve accountability
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NewsFDA approves new way to make medical imaging isotope
System will be the US’s first domestic source of molybdenum-99 for 30 years
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BusinessBMS stimulates cancer drug hopes with giant collaboration
Immunooncology pioneer will pay up to $3.6bn in hope Nektar drug will help non-responders
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NewsIllegal antibiotic combinations threaten efforts to battle antimicrobial resistance
Unapproved formulations make up two-thirds of combination therapies sold in India
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FeatureArtificial blood
Nina Notman reports on progress towards products that can, when necessary, replace donor red blood cells
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ResearchAntibiotic analogue puts researchers on path to ending herbicide drought
Research flags DNA gyrase as a new target for pesticides
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ResearchSoil search unearths new class of antibiotics
Malacidins have a novel mode of action and can kill MRSA
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ReviewVenom: killer and cure
Emma Stoye reviews a celebration of toxic critters large and small at London’s Natural History Museum
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BusinessCelgene takes a punt on M&A
Cancer specialist bags Juno therapeutics and Impact Biomedicines
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BusinessFDA new drug approvals more than doubled in 2017
The FDA approved 46 new drugs last year – the highest number in over two decades – due to factors like streamlined policies at the agency
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ResearchDeadly component of centipede venom identified
Neurotoxin allows poisonous predator to subdue a mouse within half a minute
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NewsChanging political climate threatens US cannabis research
Trump administration reverses rule protecting states with legalised marijuana
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BusinessDementia slips down pharma agenda
Pfizer, Shire, Acorda and Axovant rethink their neuroscience strategies
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ResearchNatural and unnatural peptides team up to target Ebola
New method to hunt down protease-stabilised peptide inhibitors of large proteins
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ResearchNicotine degrading enzyme could help smokers quit
Enzyme removes nicotine from blood before it can stimulate brain’s reward system
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ReviewMore molecules of murder
Aurora Walshe reviews a book that walks the line between morbid and fascinating
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ResearchFood additive may have given deadly bacterium its chance
Trehalose sugar offers competitive advantage to virulent strains of gut bacterium C. difficile
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ResearchSuzuki–Miyaura–hydrogenation targets 3D drugs
Researchers design a new pathway to make sp3 enriched drug molecules
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BusinessPharmaceuticals roundup 2017
Political influence has strongly shaped industry activity in the past year