Medicinal chemistry – Page 40
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ArticleDissolving insoluble drugs
How spray drying can help with solubility and bioavailability challenges in drug development
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ArticlePlatinum metal complexes in medicine
The history of cisplatin, the drug that is still the gold – or should that be platinum? – standard in cancer drugs
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ArticleBiosensors, wearables and virtual biotech
In a world that is racing ahead with new technologies, has the drug development process distanced itself from the patients it ultimately provides for?
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ArticleWhy biocatalysis is so on trend
Biocatalysis has come a long way from just beer – there’s an enzyme for nearly everything
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ArticleThe ever-increasing attraction of biologics
Biologics promise targeted treatments for a range of conditions – if we can overcome the technological challenges
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FeatureThe chemistry of the microbiome
Our gut bacteria are carrying out chemistry on our behalf, but without us knowing much about it. Now, scientists are starting to examine their enzymes
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FeatureThe antibiotic countdown
Where are the next generation of antibiotics going to come from? Clare Sansom looks at the pipeline
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ResearchAntimalarial plant's chlorophyll catalyses drug synthesis
New ‘green’ method makes malaria-fighting artemisinin’s synthesis faster and cheaper with industrial production planned for 2021
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NewsTracker to name and shame for failure to report clinical trial results
Developers of online tool hope that it will improve accountability
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NewsFDA approves new way to make medical imaging isotope
System will be the US’s first domestic source of molybdenum-99 for 30 years
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BusinessBMS stimulates cancer drug hopes with giant collaboration
Immunooncology pioneer will pay up to $3.6bn in hope Nektar drug will help non-responders
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NewsIllegal antibiotic combinations threaten efforts to battle antimicrobial resistance
Unapproved formulations make up two-thirds of combination therapies sold in India
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FeatureArtificial blood
Nina Notman reports on progress towards products that can, when necessary, replace donor red blood cells
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ResearchAntibiotic analogue puts researchers on path to ending herbicide drought
Research flags DNA gyrase as a new target for pesticides
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ResearchSoil search unearths new class of antibiotics
Malacidins have a novel mode of action and can kill MRSA
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ReviewVenom: killer and cure
Emma Stoye reviews a celebration of toxic critters large and small at London’s Natural History Museum
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BusinessCelgene takes a punt on M&A
Cancer specialist bags Juno therapeutics and Impact Biomedicines
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BusinessFDA new drug approvals more than doubled in 2017
The FDA approved 46 new drugs last year – the highest number in over two decades – due to factors like streamlined policies at the agency
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ResearchDeadly component of centipede venom identified
Neurotoxin allows poisonous predator to subdue a mouse within half a minute
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NewsChanging political climate threatens US cannabis research
Trump administration reverses rule protecting states with legalised marijuana