Medicinal chemistry – Page 44
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ResearchCosmetic and perfume sales staff exposed to high phthalate levels
Exposure poses potential risks for pregnant women working in retail
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FeatureStaying one step ahead of the game
Clare Sansom examines the need for agile drug development when tackling emerging viral disease outbreaks
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ResearchTagging drugs with heavy hydrogen made as easy as flicking a light switch
Photoredox reaction simplifies metabolism studies by swapping hydrogen for deuterium or tritium
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BusinessChuck Norris versus gadolinium
US action star is suing 11 drug firms for $10m, claiming his wife was poisoned by gadolinium from her MRIs
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BusinessGSK’s shingles vaccine gets thumbs up in North America
Inoculation slated to be a blockbuster
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OpinionNatural selection
Bioactive compounds don’t just inspire new synthetic strategies, they’re also the ultimate test
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NewsNew guidelines to standardise toxicity testing for nanomaterials
OECD hopes methods will ensure companies are singing from same song sheet on nanosafety
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OpinionRise of the biologics
Antibodies, RNA and gene therapy don’t necessarily compete with small molecule drugs – and they all rely on chemistry
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BusinessDrug formula change infuriates French thyroid patients
Poor communication of changes to Merck KGaA’s levothyroxine has led to complaints of side effects
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ResearchQuick test on pinprick of blood could help stop Ebola in its tracks
Portable Raspberry Pi-based device accurately detects viruses in micro droplet of whole blood
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BusinessUS to invest $160m in cancer partnership
Funds will be backed up with $55m from 11 companies to advance new cancer treatments that harness the immune system
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PodcastCinnarizine (stugeron)
Neil Withers relives a choppy (and messy) sea voyage to bring us the science of anti-seasickness drug cinnarizine
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BusinessCall for overhaul of EU rules on GMO clinical trial
Rules designed around genetically modified plants crops are holding back new cell and gene-based medicines
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WebinarFuture chemistry: exploring the possibility space
Find out how to accelerate discovery by understanding vast and complex chemistry problems with visual and predictive data modelling
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CareersVideo games are enabling discovery
Gamification is harnessing an untapped army of citizen scientists
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NewsExplainer: What is cryo-electron microscopy
The science behind the 2017 Nobel prize in chemistry
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FeatureThe long road to an HIV vaccine
A vaccine may not be available anytime soon, but its proponents are hard at work
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ResearchSuper-electrophilic ions enable selective modification of bioactive molecules
New technique will help medicinal chemists explore chemical space
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OpinionAn opportunity ignored
Dismissing ideas that were ‘not invented here’ is like walking past a $100 bill
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BusinessTakeda tightens focus on core areas with multiple deals
Japanese firm is remodelling its R&D efforts through collaboration and licensing deals, and selling off non-core businesses