Medicinal chemistry – Page 44
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ArticleDriving pharmaceutical innovation
Making drugs is neither easy nor cheap – but catalysts, flow chemistry and a knowledge of intermolecular interactions can help
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ArticleFive innovative technologies for health
How do healthcare products get from academic or start-up labs to the clinic? With a little help from places like the Centre for Process Innovation
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ArticleIs industry ready for the serialisation shake-up?
The regulation few outside of pharma have heard about
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FeatureThe chemistry of the microbiome
Our gut bacteria are carrying out chemistry on our behalf, but without us knowing much about it. Now, scientists are starting to examine their enzymes
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FeatureThe antibiotic countdown
Where are the next generation of antibiotics going to come from? Clare Sansom looks at the pipeline
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ResearchAntimalarial plant's chlorophyll catalyses drug synthesis
New ‘green’ method makes malaria-fighting artemisinin’s synthesis faster and cheaper with industrial production planned for 2021
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NewsTracker to name and shame for failure to report clinical trial results
Developers of online tool hope that it will improve accountability
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NewsFDA approves new way to make medical imaging isotope
System will be the US’s first domestic source of molybdenum-99 for 30 years
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BusinessBMS stimulates cancer drug hopes with giant collaboration
Immunooncology pioneer will pay up to $3.6bn in hope Nektar drug will help non-responders
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NewsIllegal antibiotic combinations threaten efforts to battle antimicrobial resistance
Unapproved formulations make up two-thirds of combination therapies sold in India
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FeatureArtificial blood
Nina Notman reports on progress towards products that can, when necessary, replace donor red blood cells
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ResearchAntibiotic analogue puts researchers on path to ending herbicide drought
Research flags DNA gyrase as a new target for pesticides
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ResearchSoil search unearths new class of antibiotics
Malacidins have a novel mode of action and can kill MRSA
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ReviewVenom: killer and cure
Emma Stoye reviews a celebration of toxic critters large and small at London’s Natural History Museum
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BusinessCelgene takes a punt on M&A
Cancer specialist bags Juno therapeutics and Impact Biomedicines
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BusinessFDA new drug approvals more than doubled in 2017
The FDA approved 46 new drugs last year – the highest number in over two decades – due to factors like streamlined policies at the agency
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ResearchDeadly component of centipede venom identified
Neurotoxin allows poisonous predator to subdue a mouse within half a minute
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NewsChanging political climate threatens US cannabis research
Trump administration reverses rule protecting states with legalised marijuana
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BusinessDementia slips down pharma agenda
Pfizer, Shire, Acorda and Axovant rethink their neuroscience strategies
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ResearchNatural and unnatural peptides team up to target Ebola
New method to hunt down protease-stabilised peptide inhibitors of large proteins